Hepatic lipoprotein biosynthesis.

Methods for the study of hepatic lipoprotein synthesis and secretion have been described, and the advantages of each system discussed. Attention has been focused on intact cell systems. The isolated perfused liver constitutes a standard of comparison for all others, even though it, too, has limitations. Table IV below gives our assessment of some of the advantages and disadvantages of the techniques for studying hepatic lipoprotein biosynthesis.