Literature DB >> 3724422

31P NMR detection of mobile dog brain phospholipids.

S Cerdan, V H Subramanian, M Hilberman, J Cone, J Egan, B Chance, J R Williamson.   

Abstract

The in vivo dog brain 31P NMR spectrum has a large peak in the phosphodiester region accounting for more than 35% of the total observable phosphorus metabolites. It is possible to reduce the intensity of this peak by off-resonance saturation. To characterize the nature of this peak, extracts of dog brain frozen in situ were analyzed by high resolution 31P NMR. ATP, phosphocreatine, inorganic phosphate, and phosphomonoesters were recovered in appropriate amounts in the methanol:HCl extract. However, acid soluble phosphodiesters accounted for only 8% of the observable phosphorus. More NMR observable phosphodiesters were selectively recovered following CHCl3:methanol extraction of phospholipids. These results suggest that the in vivo phosphodiester resonance has substantial contributions from a fraction of mobile brain phospholipids.

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Year:  1986        PMID： 3724422     DOI： 10.1002/mrm.1910030308

Source DB:  PubMed          Journal:  Magn Reson Med        ISSN： 0740-3194            Impact factor:   4.668


  8 in total

1.  Study of human liver disease with P-31 magnetic resonance spectroscopy.

Authors:  R Oberhaensli; B Rajagopalan; G J Galloway; D J Taylor; G K Radda
Journal:  Gut       Date:  1990-04       Impact factor: 23.059

2.  Meningioma phospholipid profiles measured by 31P nuclear magnetic resonance spectroscopy.

Authors:  L Seijo; T E Merchant; L T van der Ven; B D Minsky; T Glonek
Journal:  Lipids       Date:  1994-05       Impact factor: 1.880

3.  Glycerophosphocholine and Glycerophosphoethanolamine Are Not the Main Sources of the In Vivo (31)P MRS Phosphodiester Signals from Healthy Fibroglandular Breast Tissue at 7 T.

Authors:  Wybe J M van der Kemp; Bertine L Stehouwer; Jurgen H Runge; Jannie P Wijnen; Aart J Nederveen; Peter R Luijten; Dennis W J Klomp
Journal:  Front Oncol       Date:  2016-02-15       Impact factor: 6.244

4.  Crystal structure of Drosophila Piwi.

Authors:  Sonomi Yamaguchi; Akira Oe; Kazumichi M Nishida; Keitaro Yamashita; Asako Kajiya; Seiichi Hirano; Naoki Matsumoto; Naoshi Dohmae; Ryuichiro Ishitani; Kuniaki Saito; Haruhiko Siomi; Hiroshi Nishimasu; Mikiko C Siomi; Osamu Nureki
Journal:  Nat Commun       Date:  2020-02-12       Impact factor: 14.919

5.  Mapping an Extended Metabolic Profile of Gliomas Using High-Resolution 31P MRSI at 7T.

Authors:  Andreas Korzowski; Nina Weckesser; Vanessa L Franke; Johannes Breitling; Steffen Goerke; Heinz-Peter Schlemmer; Mark E Ladd; Peter Bachert; Daniel Paech
Journal:  Front Neurol       Date:  2021-12-23       Impact factor: 4.003

6.  Oxidative phosphorylation in creatine transporter deficiency.

Authors:  Shizhe Li; Simona Bianconi; Jan Willem van der Veen; An Dang Do; JoEllyn Stolinski; Kim M Cecil; Fady Hannah-Shmouni; Forbes D Porter; Jun Shen
Journal:  NMR Biomed       Date:  2020-09-29       Impact factor: 4.478

7.  Evidence from in vivo 31-phosphorus magnetic resonance spectroscopy phosphodiesters that exhaled ethane is a biomarker of cerebral n-3 polyunsaturated fatty acid peroxidation in humans.

Authors:  Basant K Puri; Serena J Counsell; Brian M Ross; Gavin Hamilton; Marcelo G Bustos; Ian H Treasaden
Journal:  BMC Psychiatry       Date:  2008-04-17       Impact factor: 3.630

8.  1H/31P polarization transfer at 9.4 Tesla for improved specificity of detecting phosphomonoesters and phosphodiesters in breast tumor models.

Authors:  Jannie P Wijnen; Lu Jiang; Tiffany R Greenwood; Wybe J M van der Kemp; Dennis W J Klomp; Kristine Glunde
Journal:  PLoS One       Date:  2014-07-18       Impact factor: 3.240
  8 in total

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