Superiority of tissue-culture-grown antigens over egg-grown antigens for serologic diagnosis of influenza B virus infections.

Acute and convalescent sera obtained from 10 adults and 21 children who were infected with influenza B virus were tested by hemagglutination inhibition. Of four antigens used, two tissue-culture-grown antigens were superior to either egg-grown or egg-grown, ether-treated antigens in detecting fourfold antibody rise during influenza B virus infection.