Literature DB >> 37226

A new broad-spectrum aminoglycoside antibiotic complex, sporaricin. I. Fermentation, isolation and characterization.

T Deushi, A Iwasaki, K Kamiya, T Kunieda, T Mizoguchi, M Nakayama, H Itoh, T Mori, T Oda.   

Abstract

Two new aminoglycoside antibiotics, sporaricins A (C17H35N5O5) and B (C15H32N4O4) produced by a rare actinomycetales, Saccharopolyspora hirsuta subsp. kobensis have been isolated by column chromatography on a cation-exchange resin. Sporaricin A is highly active against Gram-positive and Gram-negative bacteria including aminoglycoside-resistant strains.

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Year:  1979        PMID： 37226     DOI： 10.7164/antibiotics.32.173

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  3 in total

1.  Compound A49759, the 3-O-demethyl derivative of fortimicin A: in vitro comparison with six other aminoglycoside antibiotics.

Authors:  R N Jones; C Thornsberry; A L Barry; R R Packer; C N Baker; R E Badal
Journal:  Antimicrob Agents Chemother       Date:  1980-11       Impact factor: 5.191

2.  In vitro and in vivo antibacterial activities of K-4619, a new semisynthetic aminoglycoside.

Authors:  Y Saino; Y Hattori; T Koshi; F Kobayashi; T Oda; S Mitsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1984-08       Impact factor: 5.191

3.  In vitro and in vivo antimicrobial activities of sporaricin A, a new aminoglycoside.

Authors:  F Kobayashi; Y Saino; T Koshi; Y Hattori
Journal:  Antimicrob Agents Chemother       Date:  1980-03       Impact factor: 5.191
  3 in total

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