| Literature DB >> 3721983 |
R E Matus, C E Leifer, E G MacEwen, A I Hurvitz.
Abstract
Multiple myeloma was diagnosed in 60 dogs. Diagnosis was confirmed in each case by observation of greater than 5% plasma cells on examination of a bone marrow aspirate and detection of monoclonal gammopathy of immunoglobulin (Ig) A or IgG. Treatment with melphalan, cyclophosphamide, and prednisone was associated with long-term survival (median, 540 days). Response to therapy was significantly related to prognosis (P less than 0.01), whereas hypercalcemia and Ig light chain proteinuria (Bence Jones) were associated with shorter median survival times.Entities:
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Year: 1986 PMID： 3721983
Source DB: PubMed Journal: J Am Vet Med Assoc ISSN： 0003-1488 Impact factor: 1.936