Literature DB >> 3721511

Neurosyphilis after treatment of latent syphilis with benzathine penicillin.

J Jørgensen, G Tikjøb, K Weismann.   

Abstract

Two patients developed neurosyphilis after treatment of latent syphilis with intramuscular benzathine penicillin. The cases confirm recent investigations that show that neither benzathine penicillin nor procaine penicillin in the standard doses results in treponemicidal concentrations of penicillin in cerebrospinal fluid. Neurosyphilis can be treated effectively by intravenous benzylpenicillin infusions of 18 to 21.6 g daily for 15 days.

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Year:  1986        PMID： 3721511      PMCID： PMC1011915          DOI： 10.1136/sti.62.2.129

Source DB:  PubMed          Journal:  Genitourin Med        ISSN： 0266-4348


  9 in total

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Journal:  JAMA       Date:  1972-02       Impact factor: 56.272

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3.  Persistence of Treponema pallidum following penicillin G therapy. Report of two cases.

Authors:  E C Tramont
Journal:  JAMA       Date:  1976-11-08       Impact factor: 56.272

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Authors:  J Ducas; H G Robson
Journal:  JAMA       Date:  1981-12-04       Impact factor: 56.272

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Journal:  Arch Intern Med       Date:  1980-08

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Authors:  H R Stöckli
Journal:  Dermatologica       Date:  1982-10

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Authors:  F W Yoder
Journal:  JAMA       Date:  1975-04-21       Impact factor: 56.272

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Authors:  G Frentz; P B Nielsen; F Espersen; A Czartoryski; H Aastrup
Journal:  Eur J Clin Microbiol       Date:  1984-04       Impact factor: 3.267

9.  Penicillin concentrations in serum and cerebrospinal fluid after intramuscular injection of aqueous procaine penicillin 0.6 MU with and without probenecid.

Authors:  B T Goh; G W Smith; L Samarasinghe; V Singh; K S Lim
Journal:  Br J Vener Dis       Date:  1984-12
  9 in total
  4 in total

Review 1.  Secondary syphilitic lesions.

Authors:  Robert E Baughn; Daniel M Musher
Journal:  Clin Microbiol Rev       Date:  2005-01       Impact factor: 26.132

2.  Evaluation of the Treponema pallidum particle agglutination technique (TP.PA) in the diagnosis of neurosyphilis.

Authors:  Rita Castro; Emília S Prieto; Maria João Aguas; Maria José Manata; Júlio Botas; Carlos Araújo; Fernando Borges; Isabel Aldir; Filomena da L Exposto
Journal:  J Clin Lab Anal       Date:  2006       Impact factor: 2.352

3.  Detection of treponemal DNA in the CSF of patients with syphilis and HIV infection using the polymerase chain reaction.

Authors:  P E Hay; J R Clarke; D Taylor-Robinson; D Goldmeier
Journal:  Genitourin Med       Date:  1990-12

4.  Penicillin concentrations in cerebrospinal fluid (CSF) during repository treatment regimen for syphilis.

Authors:  P G van der Valk; E J Kraai; P C van Voorst Vader; H Haaxma-Reiche; J A Snijder
Journal:  Genitourin Med       Date:  1988-08
  4 in total

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