Literature DB >> 371737

A prospective randomized trial of vagotomy in chronic duodenal ulceration.

C G Koffman, J B Elder, I E Gillespie, P C Ganguli, D G Ostick, D J Cowley, I W Dymock, D E Tweedle, P F Schofield, C D Pengelly, M Shafiq, D R Shreeve, M Palmer.   

Abstract

In a prospective, randomized trial, 76 patients with duodenal ulceration treated by truncal vagotomy and pyloroplasty were compared with 77 patients who underwent highly selective vagotomy. A total of 149 patients was followed up for from 1 to 4 years, the average follow-up period being 2.6 years. There was no operative mortality and no significant difference in postoperative morbidity between the two groups. The incidence of recurrent ulceration was greater after highly selective vagotomy, but this difference was not statistically significant. The clinical results were comparable in each group, and although the incidence of diarrhoea and dumping was greater after vagotomy and pyloroplasty, this difference was not statistically significant.

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Year:  1979        PMID: 371737     DOI: 10.1002/bjs.1800660302

Source DB:  PubMed          Journal:  Br J Surg        ISSN: 0007-1323            Impact factor:   6.939


  4 in total

1.  Sequential ultrastructural study of mucosal innervation following parietal cell vagotomy and antrectomy.

Authors:  K A Brackett; A Crocket; S N Joffe
Journal:  Experientia       Date:  1984-08-15

2.  Prospective controlled vagotomy trial for duodenal ulcer: primary results, sequelae, acid secretion, and recurrence rates two to five years after operation.

Authors:  J Christiansen; H E Jensen; P Ejby-Poulsen; L Bardram; F W Henriksen
Journal:  Ann Surg       Date:  1981-01       Impact factor: 12.969

3.  Transgastric highly selective vagotomy (HSTRV) without drainage. Preliminary report of a new simplified procedure of treatment of duodenal ulcer.

Authors:  P C Petropoulos
Journal:  Langenbecks Arch Chir       Date:  1979

Review 4.  Current status of proximal gastric vagotomy.

Authors:  B D Schirmer
Journal:  Ann Surg       Date:  1989-02       Impact factor: 12.969

  4 in total

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