| Literature DB >> 3713205 |
Abstract
Rhesus monkeys were restrained in chairs from which their tails hung free so that their tails could be immersed into a thermos of water. Monkeys consistently kept their tails in 38-40 degrees C water for at least 20 sec, but withdrew them from 55 degrees C water in 1-4 sec. Tail withdrawal latencies from 55 degrees C water remained consistent over a period of 3 hr. Morphine produced dose-dependent increases in tail withdrawal latencies from 55 degrees C water, whereas pentobarbital, haloperidol, and phencyclidine did not increase tail withdrawal latencies except at doses that produced marked sedation.Entities:
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Year: 1986 PMID： 3713205 DOI： 10.1016/0160-5402(86)90056-2
Source DB: PubMed Journal: J Pharmacol Methods ISSN： 0160-5402