Literature DB >> 3711218

Rapid determination of p-hydroxylated methamphetamine metabolites by column liquid chromatography-electrochemistry.

K Shimosato, M Tomita, I Ijiri.   

Abstract

A method for electrochemical determination of p-hydroxymethamphetamine and p-hydroxyamphetamine in human urine was investigated by column liquid chromatography. A rapid and simple extraction of these substances from urine was performed using a solid-phase extraction column. The detection limit for quantitation was approximately 50 pg for the metabolites. The simplicity and sensitivity of this method allows for analysis of these metabolites in the fields of toxicology and forensic medicine.

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Year:  1986        PMID: 3711218     DOI: 10.1016/s0378-4347(00)80783-5

Source DB:  PubMed          Journal:  J Chromatogr


  2 in total

1.  Urinary excretion of p-hydroxylated methamphetamine metabolites in man. I. A method for determination by high-performance liquid chromatography-electrochemistry.

Authors:  K Shimosato; M Tomita; I Ijiri
Journal:  Arch Toxicol       Date:  1986-10       Impact factor: 5.153

2.  Novel biomarkers of prenatal methamphetamine exposure in human meconium.

Authors:  Teresa R Gray; Tamsin Kelly; Linda L LaGasse; Lynne M Smith; Chris Derauf; William Haning; Penny Grant; Rizwan Shah; Amelia Arria; Arthur Strauss; Barry M Lester; Marilyn A Huestis
Journal:  Ther Drug Monit       Date:  2009-02       Impact factor: 3.681

  2 in total

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