Literature DB >> 3709599

A phase II study of tamoxifen in ovarian cancer.

M L Slevin, V J Harvey, R J Osborne, J H Shepherd, C J Williams, G M Mead.   

Abstract

A phase II study of tamoxifen was conducted in 22 patients with stage III and IV ovarian cancer who had failed chemotherapy and who had evaluable disease. Tamoxifen was administered at a dose of 20 mg twice daily continuously until evidence of progression. Twenty-one patients had progression of disease within 3 months and one patient had stable disease for 6 months. There were no objective responses to this treatment.

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Year:  1986        PMID: 3709599     DOI: 10.1016/0277-5379(86)90396-2

Source DB:  PubMed          Journal:  Eur J Cancer Clin Oncol        ISSN: 0277-5379


  8 in total

1.  Antiestrogen therapy in recurrent ovarian cancer resulting in 28 months of stable disease: a case report and review of the literature.

Authors:  Rajul Kothari; Peter Argenta; Jeffrey Fowler; Jori Carter; William Shimp
Journal:  Arch Oncol       Date:  2010

Review 2.  Tamoxifen for relapse of ovarian cancer.

Authors:  Chris Williams; Iveta Simera; Andrew Bryant
Journal:  Cochrane Database Syst Rev       Date:  2010-03-17

Review 3.  Hormone response in ovarian cancer: time to reconsider as a clinical target?

Authors:  Francesmary Modugno; Robin Laskey; Ashlee L Smith; Courtney L Andersen; Paul Haluska; Steffi Oesterreich
Journal:  Endocr Relat Cancer       Date:  2012-11-09       Impact factor: 5.678

Review 4.  New insights on the role of hormonal therapy in ovarian cancer.

Authors:  Fiona Simpkins; Arlene Garcia-Soto; Joyce Slingerland
Journal:  Steroids       Date:  2013-02-08       Impact factor: 2.668

5.  Tamoxifen in refractory ovarian cancer: the use of a loading dose schedule.

Authors:  R J Osborne; S T Malik; M L Slevin; V J Harvey; J Spona; H Salzer; C J Williams
Journal:  Br J Cancer       Date:  1988-01       Impact factor: 7.640

6.  Oestrogen receptor expression and the effects of oestrogen and tamoxifen on the growth of human ovarian carcinoma cell lines.

Authors:  S P Langdon; M M Hawkes; S S Lawrie; R A Hawkins; A L Tesdale; A J Crew; W R Miller; J F Smyth
Journal:  Br J Cancer       Date:  1990-08       Impact factor: 7.640

7.  The clinical activity of cyproterone acetate in advanced ovarian carcinoma. A London Gynaecology Oncology Group Study.

Authors:  P Thompson; P Wilson; R Osborne; M Slevin; F Wiltshaw; P Blake; P Harper; R Coleman; C Williams; J Sweetenham
Journal:  Br J Cancer       Date:  1991-11       Impact factor: 7.640

Review 8.  Hormone therapy for ovarian cancer: Emphasis on mechanisms and applications (Review).

Authors:  Hongyi Li; Yu Liu; Yang Wang; Xia Zhao; Xiaorong Qi
Journal:  Oncol Rep       Date:  2021-08-26       Impact factor: 3.906

  8 in total

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