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Literature DB >> 3709479

Methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid.

Abstract

We have found several similarities between tannic acid and grain dust extract prepared with methanol. Both formed a precipitate with IgG, and these interactions were inhibited by albumin. In addition, both preparations fixed complement; this activity was heat stable and was removed by prior adsorption of the preparations with hide powder. Adsorption with polyvinyl polypyrrolidone reduced the complement-fixing activity of tannic acid but not that of the methanol grain dust extract. The similarities between tannic acid and the methanol grain dust extract are consistent with the presence of a tannin or tanninlike material in grain dust.

Entities: Chemical

Mesh：

Substances：

Year: 1986 PMID： 3709479 PMCID： PMC1474384 DOI： 10.1289/ehp.8666155

Source DB: PubMed Journal: Environ Health Perspect ISSN： 0091-6765 Impact factor: 9.031

16 in total

1. Conversion of C3 and consumption of hemolytic complement by extracts of airborne grain dust.

Authors: S A Olenchock; J C Mull; P C Major
Journal: Chest Date: 1979-02 Impact factor: 9.410

2. Comparison of respiratory variables in grain elevator workers and civic outside workers of Thunder Bay, Canada.

Authors: I Broder; S Mintz; M Hutcheon; P Corey; F Silverman; G Davies; A Leznoff; L Peress; P Thomas
Journal: Am Rev Respir Dis Date: 1979-02

3. Precipitation of serum proteins by extracts of cotton dust and stems. Identification of beta-lipoprotein and production of specific antibodies.

Authors: S A Kutz; M S Mentnech; S A Olenchock; P C Major
Journal: Environ Res Date: 1980-08 Impact factor: 6.498

4. Immunological studies of grain dust.

Authors: S A Olenchock; P C Major
Journal: J Environ Pathol Toxicol Date: 1979 May-Jun

5. In vitro alternative and classical activation of complement by extracts of cotton mill dust: a possible mechanism in the pathogenesis of byssinosis.

Authors: T G Mundie; R J Boackle; S K Ainsworth
Journal: Environ Res Date: 1983-10 Impact factor: 6.498

Methanol extract of grain dust shows complement fixing activity and other characteristics similar to tannic acid.

1. Conversion of C3 and consumption of hemolytic complement by extracts of airborne grain dust.

2. Comparison of respiratory variables in grain elevator workers and civic outside workers of Thunder Bay, Canada.

3. Precipitation of serum proteins by extracts of cotton dust and stems. Identification of beta-lipoprotein and production of specific antibodies.

4. Immunological studies of grain dust.

5. In vitro alternative and classical activation of complement by extracts of cotton mill dust: a possible mechanism in the pathogenesis of byssinosis.

6. Extracts of airborne grain dusts activate alternative and classical complement pathways.

7. Epidemiologic health survey of grain elevator workers in British Columbia.

8. Effect of layoff and rehire on respiratory variables of grain elevator workers.

9. Antibody-independent complement activation by cardroom cotton dust.

10. Chronic bronchitis and decreased forced expiratory flow rates in lifetime nonsmoking grain workers.

1. Recommendations for reducing the effect of grain dust on the lungs. Canadian Thoracic Society Standards Committee.

Review 2. Etiology and pathogenesis of airway disease in children and adults from rural communities.