Literature DB >> 3708910

CRP and neutrophils: functional effects and complex uptake.

E G Shephard, R Anderson, A F Strachan, S H Kühn, F C De Beer.   

Abstract

The uptake of C-reactive protein (CRP)-pneumococcal C-polysaccharide (CPS) complexes by neutrophils was studied. A specific CRP dependent mechanism of uptake was demonstrated. This promoted CPS (complexed to CRP) clearance which was further enhanced by additional complement activation. Physiological concentrations of low density lipoprotein inhibited entry of complexed CPS into neutrophils but had no effect on entry of CRP alone. Pure human CRP was shown to have no effect on neutrophil chemotaxis and oxidative metabolism.

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Year:  1986        PMID： 3708910      PMCID： PMC1577559     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  37 in total

1.  Isolation of C-reactive protein by affinity chromatography.

Authors:  M B Pepys; A C Dash; M J Ashley
Journal:  Clin Exp Immunol       Date:  1977-10       Impact factor: 4.330

2.  Characterization of C-reactive protein and the complement subcomponent C1t as homologous proteins displaying cyclic pentameric symmetry (pentraxins).

Authors:  A P Osmand; B Friedenson; H Gewurz; R H Painter; T Hofmann; E Shelton
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

3.  Complement-induced solubilization of C-reactive protein-pneumococcal C-polysaccharide precipitates: evidence for covalent binding of complement proteins to C-reactive protein and to pneumococcal C-polysaccharide.

Authors:  J E Volanakis
Journal:  J Immunol       Date:  1982-06       Impact factor: 5.422

4.  Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies.

Authors:  C B Laurell
Journal:  Anal Biochem       Date:  1966-04       Impact factor: 3.365

Review 5.  C-reactive protein reactivity with complement and effects on phagocytosis.

Authors:  C Mold; T W Du Clos; S Nakayama; K M Edwards; H Gewurz
Journal:  Ann N Y Acad Sci       Date:  1982       Impact factor: 5.691

6.  A role for C-reactive protein in the complement-mediated stimulation of human neutrophils by type 27 Streptococcus pneumoniae.

Authors:  K M Edwards; H Gewurz; T F Lint; C Mold
Journal:  J Immunol       Date:  1982-06       Impact factor: 5.422

7.  Isolation and characterization of C-reactive protein and serum amyloid P component in the rat.

Authors:  F C de Beer; M L Baltz; E A Munn; A Feinstein; J Taylor; C Bruton; J R Clamp; M B Pepys
Journal:  Immunology       Date:  1982-01       Impact factor: 7.397

8.  Localization of C-reactive protein in inflammatory lesions of experimental allergic encephalomyelitis.

Authors:  T W Du Clos; C Mold; P Y Paterson; J Alroy; H Gewurz
Journal:  Clin Exp Immunol       Date:  1981-03       Impact factor: 4.330

9.  C-reactive protein mediates the solubilization of nuclear DNA by complement in vitro.

Authors:  F A Robey; K D Jones; A D Steinberg
Journal:  J Exp Med       Date:  1985-06-01       Impact factor: 14.307

10.  Studies of acute phase protein. I. An immunohistochemical method for the localization of Cx-reactive protein in rabbits. Association with necrosis in local inflammatory lesions.

Authors:  I KUSHNER; M H KAPLAN
Journal:  J Exp Med       Date:  1961-12-01       Impact factor: 14.307
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  6 in total

1.  Binding of human C-reactive protein to monocytes: analysis by flow cytometry.

Authors:  S P Ballou; R P Cleveland
Journal:  Clin Exp Immunol       Date:  1991-05       Impact factor: 4.330

2.  C-reactive protein in patients with lymphatic filariasis: increased expression on lymphocytes in chronic lymphatic obstruction.

Authors:  R B Lal; R R Dhawan; R M Ramzy; R M Farris; A A Gad
Journal:  J Clin Immunol       Date:  1991-01       Impact factor: 8.317

3.  Pentraxin binding to isolated rat liver nuclei.

Authors:  E G Shephard; P J Smith; S Coetzee; A F Strachan; F C de Beer
Journal:  Biochem J       Date:  1991-10-01       Impact factor: 3.857

4.  Neutrophil lysosomal degradation of human CRP: CRP-derived peptides modulate neutrophil function.

Authors:  E G Shephard; R Anderson; S M Beer; C E Van Rensburg; F C de Beer
Journal:  Clin Exp Immunol       Date:  1988-07       Impact factor: 4.330

5.  Stimulation of human neutrophils, monocytes, and platelets by modified C-reactive protein (CRP) expressing a neoantigenic specificity.

Authors:  L A Potempa; J M Zeller; B A Fiedel; C M Kinoshita; H Gewurz
Journal:  Inflammation       Date:  1988-08       Impact factor: 4.092

6.  Binding sites for C-reactive protein on human monocytes are distinct from IgG Fc receptors.

Authors:  J M Zeller; B M Kubak; H Gewurz
Journal:  Immunology       Date:  1989-05       Impact factor: 7.397
  6 in total

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