Literature DB >> 3707969

Hb J-Antakya or alpha 2 beta (2)65(E9)Lys----Met in a Turkish family and Hb complutense or alpha 2 beta (2)127(H5)Gln----Glu in a Spanish family; correction of a previously published identification.

T H Huisman, J B Wilson, A Kutlar, K G Yang, S S Chen, B B Webber, C Altay, A V Martinez.   

Abstract

Almost 10 years ago we reported in this journal the characterization of Hb Hacettepe or alpha 2 beta (2)127(H5)Gln----Glu. Unfortunately, we have to conclude that the original characterization of this Turkish variant was in error. The corrected data are presented in this short communication. The variant (alpha 2 beta (2)65(E9)Lys----Met) was (re)named Hb J-Antakya, after the city where the family resides. An abnormal Hb, observed in a Spanish family and named Hb Complutense, had the beta 127 Gln----Glu substitution, erroneously assigned to the Turkish variant.

Entities:  

Mesh:

Substances:

Year:  1986        PMID: 3707969     DOI: 10.1016/0167-4838(86)90178-0

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  1 in total

1.  Rapid molecular characterization of mutations leading to unstable hemoglobin beta-chain variants.

Authors:  E Girodon; N Ghanem; M Vidaud; J Riou; J Martin; F Galactéros; M Goossens
Journal:  Ann Hematol       Date:  1992-10       Impact factor: 3.673

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.