Photic retinopathy from the operating room microscope.

Photic retinopathy was produced in two patients after a 60-minute exposure to light from an operating room microscope (Zeiss OpMi 6). The first patient had a blind eye with clear (phakic) media and a normal-appearing retina. A 60-minute exposure produced an oval gray lesion in the posterior pole at the level of the pigment epithelium. With an ultraviolet-400 filter added for a second exposure, a second lesion was produced. The second patient received a 60-minute exposure (without an ultraviolet filter) 72 hours before enucleation for a malignant melanoma. This produced photic retinopathy that resulted in a slight decrease in central visual acuity and a dense paracentral scotoma. This conclusively establishes a cause-and-effect relationship between exposure to the light from an operating room microscope and a retinal lesion in the human eye.