Literature DB >> 370582

Mutagenicity of aliphatic nitrosamines in Salmonella typhimurium.

T K Rao, J A Young, W Lijinsky, J L Epler.   

Abstract

25 aliphatic nitrosamines were examined in the Ames assay for bacterial mutagens, using rat liver "S-9" for activation. Of them, 8 carcinogens were mutagenic and 5 non-carcinogens were not mutagenic. However, 2 compounds not carcinogenic in rats were mutagenic and 9 carcinogens were not mutagenic, including 6 that are liver carcinogens in rats.

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Year:  1979        PMID： 370582     DOI： 10.1016/0165-1218(79)90002-8

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  6 in total

1.  Alcoholdehydrogenase as an activating enzyme for N-nitrosodiethanolamine (NDELA): in vitro activation of NDELA to a potent mutagen in Salmonella typhimurium.

Authors:  G Eisenbrand; E Denkel; B Pool
Journal:  J Cancer Res Clin Oncol       Date:  1984       Impact factor: 4.553

2.  Studies on the metabolic activation of diethanolnitrosamine in animal-mediated and in vitro assays using Escherichia coli K-12 343/113 as an indicator.

Authors:  S Knasmüller; G Stehlik; G Mohn
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

3.  Mutagenicity of 4,4'-methylenedianiline derivatives in the Salmonella histidine reversion assay.

Authors:  T K Rao; G F Dorsey; B E Allen; J L Epler
Journal:  Arch Toxicol       Date:  1982-03       Impact factor: 5.153

4.  Interaction of mutagenic spermidine-nitrous acid reaction products with uvr- and recA-dependent repair systems in Salmonella.

Authors:  M Murphey-Corb; H L Kong; M L Murray
Journal:  J Bacteriol       Date:  1980-04       Impact factor: 3.490

5.  Carcinogenesis in F-344 rats by nitrosobis(2-oxopropyl)amine and related compounds administered in drinking water.

Authors:  W Lijinsky; J E Saavedra; M D Reuber
Journal:  J Cancer Res Clin Oncol       Date:  1984       Impact factor: 4.553

6.  Cytogenetic effects of N-nitrosodiethanolamine (NDELA) and NDELA-monoacetate in human lymphocytes.

Authors:  U Dittberner; G Eisenbrand; H Zankl
Journal:  J Cancer Res Clin Oncol       Date:  1988       Impact factor: 4.553
  6 in total

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