Literature DB >> 3704106

Small bowel ulceration in patients receiving non-steroidal anti-inflammatory drugs for rheumatoid arthritis.

R Madhok, J A MacKenzie, F D Lee, F E Bruckner, T R Terry, R D Sturrock.   

Abstract

Evidence is presented for a non-specific ulcerative process in the small bowel of patients with rheumatoid arthritis. All three cases presented with lower gastrointestinal bleeding; on withdrawal of non-steroidal anti-inflammatory drugs no further bleeding occurred. Non-steroidal anti-inflammatory drugs may lead to small bowel ulceration in inhibiting mucosal glycoprotein synthesis and increasing intestinal permeability.

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Year:  1986        PMID： 3704106

Source DB:  PubMed          Journal:  Q J Med        ISSN： 0033-5622


  16 in total

Review 1.  Gastrointestinal complications of nonsteroidal anti-inflammatory drugs.

Authors:  R R Babb
Journal:  West J Med       Date:  1992-10

Review 2.  Small intestinal mucosal protection mechanisms and their importance in rheumatology.

Authors:  S O'Mahony; A Ferguson
Journal:  Ann Rheum Dis       Date:  1991-05       Impact factor: 19.103

3.  Small bowel enteroscopy in undiagnosed gastrointestinal blood loss.

Authors:  A J Morris; L A Wasson; J F MacKenzie
Journal:  Gut       Date:  1992-07       Impact factor: 23.059

4.  [Not Available].

Authors:  E Hackenthal
Journal:  Schmerz       Date:  1990-09       Impact factor: 1.107

5.  Protective effect of metronidazole on uncoupling mitochondrial oxidative phosphorylation induced by NSAID: a new mechanism.

Authors:  A Z Leite; A M Sipahi; A O Damião; A M Coelho; A T Garcez; M C Machado; C A Buchpiguel; F P Lopasso; M L Lordello; C L Agostinho; A A Laudanna
Journal:  Gut       Date:  2001-02       Impact factor: 23.059

6.  Gastrointestinal safety of an extended-release, nondeformable, oral dosage form (OROS: a retrospective study.

Authors:  Dorsey M Bass; Mary Prevo; Deborah S Waxman
Journal:  Drug Saf       Date:  2002       Impact factor: 5.606

7.  Ileocaecal perforation and bleeding--are non-steroidal anti-inflammatory drugs (NSAIDs) responsible?

Authors:  K C Saw; C R Quick; A F Higgins
Journal:  J R Soc Med       Date:  1990-02       Impact factor: 5.344

8.  Diaphragm disease: pathology of disease of the small intestine induced by non-steroidal anti-inflammatory drugs.

Authors:  J Lang; A B Price; A J Levi; M Burke; J M Gumpel; I Bjarnason
Journal:  J Clin Pathol       Date:  1988-05       Impact factor: 3.411

9.  Non-steroidal anti-inflammatory drug-induced small bowel injuries identified by double-balloon endoscopy.

Authors:  Yoshikazu Hayashi; Hironori Yamamoto; Hiroto Kita; Keijiro Sunada; Hiroyuki Sato; Tomonori Yano; Michiko Iwamoto; Yutaka Sekine; Tomohiko Miyata; Akiko Kuno; Takaaki Iwaki; Yoshiyuki Kawamura; Hironari Ajibe; Kenichi Ido; Kentaro Sugano
Journal:  World J Gastroenterol       Date:  2005-08-21       Impact factor: 5.742

10.  Duodenal diaphragmlike stricture induced by acetylsalicylic acid.

Authors:  G H Blinder; M L Hautekeete; J P Holvoet; M M Kockx; H K Hubens
Journal:  Dig Dis Sci       Date:  1994-06       Impact factor: 3.199
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