Retinoblastoma in Lebanon.

The data on 58 patients with retinoblastoma managed at the American University of Beirut, Medical Center over the last 35 years is reviewed. The epidemiology, genetics and clinical features of this tumor appear to be the same in the Middle-East as well as the rest of the world. The notable difference between the data in this study and that from other studies is the marked delay in diagnosis of the tumor in this part of the world leading to a higher incidence of extraocular extension, a more advanced stage of the disease and poorer survival rates. This seems to be a feature of medically underdeveloped societies. Increased public awareness of the early signs and symptoms of the disease, as well as routine fundoscopy on all infants are advocated to improve early detection, leading to improved survival rates and prevention of unnecessary enucleations.