Literature DB >> 3699450

Ethanol blocks tetanic and calcium-induced long-term potentiation in the hippocampal slice.

J G Sinclair, G F Lo.   

Abstract

Long-term potentiation (LTP) of the CA1 population spike in the hippocampal slice was produced by a tetanic stimulus in the stratum radiatum or by doubling the calcium concentration in the medium to 4 mM for 10 min. Ethanol (0.1 M) antagonized both tetanic- and ethanol-induced LTP. Since the hippocampus is known to be involved with memory, and ethanol interferes with memory and the production of LTP, the results are consistent with the notion that LTP may be related to memory processes.

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Year:  1986        PMID: 3699450     DOI: 10.1016/0306-3623(86)90144-8

Source DB:  PubMed          Journal:  Gen Pharmacol        ISSN: 0306-3623


  19 in total

1.  Chronic nicotine treatment differentially modifies acute nicotine and alcohol actions on GABA(A) and glutamate receptors in hippocampal brain slices.

Authors:  William R Proctor; Peter Dobelis; Anna T Moritz; Peter H Wu
Journal:  Br J Pharmacol       Date:  2011-03       Impact factor: 8.739

2.  Metabotropic Glutamate Receptors in Alcohol Use Disorder: Physiology, Plasticity, and Promising Pharmacotherapies.

Authors:  Max E Joffe; Samuel W Centanni; Anel A Jaramillo; Danny G Winder; P Jeffrey Conn
Journal:  ACS Chem Neurosci       Date:  2018-06-08       Impact factor: 4.418

3.  Acute ethanol suppresses glutamatergic neurotransmission through endocannabinoids in hippocampal neurons.

Authors:  Balapal S Basavarajappa; Ipe Ninan; Ottavio Arancio
Journal:  J Neurochem       Date:  2008-09-15       Impact factor: 5.372

4.  Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression.

Authors:  Jennifer G Bray; Kenneth C Reyes; Amanda J Roberts; Richard M Ransohoff; Donna L Gruol
Journal:  Neuropharmacology       Date:  2012-11-16       Impact factor: 5.250

Review 5.  Ethanol modulation of synaptic plasticity.

Authors:  Brian A McCool
Journal:  Neuropharmacology       Date:  2010-12-31       Impact factor: 5.250

6.  Ethanol exposure in early adolescence inhibits intrinsic neuronal plasticity via sigma-1 receptor activation in hippocampal CA1 neurons.

Authors:  Jilla Sabeti
Journal:  Alcohol Clin Exp Res       Date:  2011-02-11       Impact factor: 3.455

7.  Memory encoding and retrieval on the ascending and descending limbs of the blood alcohol concentration curve.

Authors:  Hedvig Söderlund; Elizabeth S Parker; Barbara L Schwartz; Endel Tulving
Journal:  Psychopharmacology (Berl)       Date:  2005-10-19       Impact factor: 4.530

Review 8.  Adolescent alcohol exposure and persistence of adolescent-typical phenotypes into adulthood: a mini-review.

Authors:  Linda Patia Spear; H Scott Swartzwelder
Journal:  Neurosci Biobehav Rev       Date:  2014-05-09       Impact factor: 8.989

9.  Nitrendipine prevents the decrease caused by chronic ethanol intake in the maintenance of tetanic long-term potentiation.

Authors:  T L Ripley; H J Little
Journal:  Exp Brain Res       Date:  1995       Impact factor: 1.972

Review 10.  The effects of abused drugs on adolescent development of corticolimbic circuitry and behavior.

Authors:  J M Gulley; J M Juraska
Journal:  Neuroscience       Date:  2013-05-24       Impact factor: 3.590

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