| Literature DB >> 3698925 |
C J Shaar, E L Grinnan, W G Short, J G Powell, N Bryan, K G Bemis, F C Tinsley.
Abstract
The recombinant DNA-derived 20,000-dalton variant of N-terminal methionyl human growth hormone (20K-Met-hGH) had a hyperglycemic effect in fasted dogs when injected 11 hours prior to an oral glucose tolerance test (OGTT). These results reported here suggest that 20K-Met-hGH can induce glucose intolerance in dogs similar to that produced by recombinant DNA-derived 22,000 dalton N-terminal methionyl human growth hormone (22K-Met-hGH) and the normal pituitary-source human growth hormone (22K-hGH).Entities:
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Year: 1986 PMID: 3698925 DOI: 10.1080/07435808609023651
Source DB: PubMed Journal: Endocr Res ISSN: 0743-5800 Impact factor: 1.720