Literature DB >> 369854

The delayed effect of sodium valproate on the photoconvulsive response in man.

A J Rowan, C D Binnie, C A Warfield, H Meinardi, J W Meijer.   

Abstract

The acute effect of a single oral dose of sodium valproate on the photoconvulsive response has been studied. In 7 of 9 patients naive to this drug photosensitivity was abolished or reduced. A similar effect was seen in only 2 of 7 already receiving chronic sodium valproate therapy. The effect appeared 1 to 5 hr (mean, 3 hr) after attainment of peak sodium valproate concentration and lasted up to 5 days.

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Year:  1979        PMID: 369854     DOI: 10.1111/j.1528-1157.1979.tb04776.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN: 0013-9580            Impact factor:   5.864


  16 in total

1.  Extended-release formulations of antiepileptic drugs: rationale and comparative value.

Authors:  Emilio Perucca
Journal:  Epilepsy Curr       Date:  2009 Nov-Dec       Impact factor: 7.500

Review 2.  Antiepileptic drug treatment in the nineties in The Netherlands.

Authors:  D G Kasteleijn-Nolstlt Trenité; P M Edelbroek
Journal:  Pharm World Sci       Date:  1997-04

3.  Overuse of monitoring of blood concentrations of antiepileptic drugs.

Authors:  D W Chadwick
Journal:  Br Med J (Clin Res Ed)       Date:  1987-03-21

Review 4.  Epilepsy.

Authors:  D Chadwick
Journal:  J Neurol Neurosurg Psychiatry       Date:  1994-03       Impact factor: 10.154

Review 5.  Optimisation of antiepileptic drug therapy. The importance of serum drug concentration monitoring.

Authors:  E Yukawa
Journal:  Clin Pharmacokinet       Date:  1996-08       Impact factor: 6.447

6.  Electroencephalographic and behavioural effects of sodium valproate in patients with photosensitive epilepsy. A single dose trial.

Authors:  M S Myslobodsky; M Mintz; R Douglas
Journal:  J Neurol       Date:  1980       Impact factor: 4.849

7.  Methods of assessment of antiepileptic drugs.

Authors:  N Milligan; A Richens
Journal:  Br J Clin Pharmacol       Date:  1981-05       Impact factor: 4.335

8.  Intra-daily oscillations in dipropylacetic acid plasma levels with two or three daily doses of dipropylacetamide in epileptic patients.

Authors:  F Pisani; E Spina; C Trunfio; A Fazio; G Oteri; R Di Perri
Journal:  Ital J Neurol Sci       Date:  1983-06

9.  Plasma protein-binding and CSF concentrations of valproic acid in man following acute oral dosing.

Authors:  W G Rapeport; A D Mendelow; G French; P MacPherson; E Teasdale; E Agnew; G G Thompson; M J Brodie
Journal:  Br J Clin Pharmacol       Date:  1983-10       Impact factor: 4.335

Review 10.  Concentration-effect relationships of valproic acid.

Authors:  D W Chadwick
Journal:  Clin Pharmacokinet       Date:  1985 Mar-Apr       Impact factor: 6.447

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