Literature DB >> 3694616

Phenylephrine-induced reversible cataract in the mouse.

C M Claoué1.   

Abstract

Topical 10% phenylephrine will produce lens opacities in several strains of mouse. These lens opacities resolve spontaneously within 24 hours, leaving an apparently normal eye. Phenylephrine-induced lens opacification in the mouse can be prevented by covering the eye with ointment, suggesting that the underlying mechanism is transcorneal dehydration.

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Year:  1987        PMID： 3694616      PMCID： PMC1291091          DOI： 10.1177/014107688708001112

Source DB:  PubMed          Journal:  J R Soc Med        ISSN： 0141-0768            Impact factor:   18.000


  4 in total

1.  Production of unilateral reversible cataracts in the hamster.

Authors:  F T FRAUNFELDER; R P BURNS
Journal:  Proc Soc Exp Biol Med       Date:  1962-05

2.  Acute reversible lens opacity: caused by drugs, cold, anoxia, asphyxia, stress, death and dehydration.

Authors:  F T Fraunfelder; R P Burns
Journal:  Exp Eye Res       Date:  1970-07       Impact factor: 3.467

3.  Effect of lid closure in drug-induced experimental cataracts.

Authors:  F T Fraunfelder; R P Burns
Journal:  Arch Ophthalmol       Date:  1966-10

Review 4.  The physiologic and pharmacologic factors protecting the lens transparency and the update approach to the prevention of experimental cataracts: a review.

Authors:  G Auricchio; T Libondi
Journal:  Metab Pediatr Syst Ophthalmol       Date:  1983
  4 in total

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