Literature DB >> 3693253

A model for tumorigenicity and metastatic potential: growth in 1.0% agar cultures.

T Saiga1, T Ohbayashi, K Tabuchi, O Midorikawa.   

Abstract

We developed a method to determine the amount of work performed by cells through cell division in 1.0% agar cultures. There was no correlation between the cloning efficiencies of 1.0 and 0.3% agar cultures. Growth in 1.0% agar cultures correlated well with such malignant properties as tumorigenicity and the invasive and metastatic potentials. Our method revealed that metastatic MC and F cell lines possess different means of taking advantage of energy to proliferate against an environmental pressure from those possessed by nontumorigenic (ME and T-C3H) cell strain/line or nonmetastatic but tumorigenic (L,MR, and magc1) cell lines.

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Year:  1987        PMID: 3693253     DOI: 10.1007/bf02620964

Source DB:  PubMed          Journal:  In Vitro Cell Dev Biol        ISSN: 0883-8364


  16 in total

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Authors:  L A Liotta
Journal:  Cancer Res       Date:  1986-01       Impact factor: 12.701

2.  Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium.

Authors:  V H Freedman; S I Shin
Journal:  Cell       Date:  1974-12       Impact factor: 41.582

3.  Tumor growth and neovascularization: an experimental model using the rabbit cornea.

Authors:  M A Gimbrone; R S Cotran; S B Leapman; J Folkman
Journal:  J Natl Cancer Inst       Date:  1974-02       Impact factor: 13.506

4.  Characterization of stable spontaneous metastatic variant lines of RSV-transformed mouse fibroblasts.

Authors:  M F Di Renzo; S Bretti
Journal:  Int J Cancer       Date:  1982-12-15       Impact factor: 7.396

5.  Correlation of anchorage-independent growth with tumorigenicity of chemically transformed mouse epidermal cells.

Authors:  N H Colburn; W F Bruegge; J R Bates; R H Gray; J D Rossen; W H Kelsey; T Shimada
Journal:  Cancer Res       Date:  1978-03       Impact factor: 12.701

6.  An improved method for calculating colony forming ability in soft agar with special reference to malignancy.

Authors:  T Saiga; T Adachi; E Okamoto; O Midorikawa
Journal:  Experientia       Date:  1981-03-15

7.  Protein synthesis but not DNA synthesis is required for tumor cell invasion in vitro.

Authors:  U P Thorgeirsson; T Turpeenniemi-Hujanen; L M Neckers; D W Johnson; L A Liotta
Journal:  Invasion Metastasis       Date:  1984

8.  Human muscle: a model for the study of human neoplasia.

Authors:  J C Petricciani; I Levenbook; R Locke
Journal:  Invest New Drugs       Date:  1983       Impact factor: 3.850

9.  Gradation of carcinogen-induced capacity for anchorage-independent growth in cultured rat liver epithelial cells.

Authors:  M S Tsao; H S Earp; J W Grisham
Journal:  Cancer Res       Date:  1985-09       Impact factor: 12.701

10.  Colony morphology and growth in agarose as tests for spontaneous neoplastic transformation in vitro.

Authors:  R W Tucker; K K Sanford; S L Handleman; G M Jones
Journal:  Cancer Res       Date:  1977-05       Impact factor: 12.701

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  4 in total

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4.  Low dose amiodarone reduces tumor growth and angiogenesis.

Authors:  Eliana Steinberg; Arnon Fluksman; Chalom Zemmour; Katerina Tischenko; Adi Karsch-Bluman; Yifat Brill-Karniely; Amy E Birsner; Robert J D'Amato; Ofra Benny
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  4 in total

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