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Literature DB >> 3691611

Excretion of oxazepam in breast milk.

Abstract

Oxazepam was measured in plasma and breast milk during 3 days of medication and 10 and 34 h after the last dose. The half-life estimated from levels in plasma and milk was approximately 12 hours. Less than 1/1000 of the maternal dose would have been excreted in 1 l breast milk.

Entities: Chemical

Mesh：

Substances：
Oxazepam

Year: 1987 PMID： 3691611 DOI： 10.1007/bf00544570

Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953

8 in total

1. Disposition of three benzodiazepines after single oral administration in man.

Authors: M Wretlind; A Pilbrant; A Sundwall; J Vessman
Journal: Acta Pharmacol Toxicol (Copenh) Date: 1977-01

2. Benzodiazepine activity: is interaction with the glycine receptor, as evidenced by displacement of strychnine binding, a useful criterion?

Authors: P Hunt; J P Raynaud
Journal: J Pharm Pharmacol Date: 1977-07 Impact factor: 3.765

3. Pharmacokinetics of oxazepam in healthy volunteers.

Authors: G Alván; B Siwers; J Vessman
Journal: Acta Pharmacol Toxicol (Copenh) Date: 1977-01

4. Determination of oxazepam in serum and urine by electron capture gas chromatography.

Authors: J Vessman; G Freij; S Strömberg
Journal: Acta Pharm Suec Date: 1972-11

5. [Oxazepam withdrawal in the neonatal period].

Authors: A Rane; A Sundwall; G Tomson
Journal: Lakartidningen Date: 1979-11-28

6. Placental passage of oxazepam and its metabolism in mother and newborn.

Authors: G Tomson; N O Lunell; A Sundwall; A Rane
Journal: Clin Pharmacol Ther Date: 1979-01 Impact factor: 6.875

7. An examination of acid-base equilibria of 1,4-benzodiazepines by spectrophotometry.

Authors: J Barrett; W F Smyth; I E Davidson
Journal: J Pharm Pharmacol Date: 1973-05 Impact factor: 3.765

Review 8. Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations.

Authors: J H Kanto
Journal: Drugs Date: 1982-05 Impact factor: 9.546

8 in total

1. Excretion of temazepam in breast milk.

Authors: T H Lebedevs; R E Wojnar-Horton; P Yapp; M J Roberts; L J Dusci; L P Hackett; K F Ilett
Journal: Br J Clin Pharmacol Date: 1992-02 Impact factor: 4.335

2. Excretion of diazepam and its metabolites in human milk during withdrawal from combination high dose diazepam and oxazepam.

Authors: L J Dusci; S M Good; R W Hall; K F Ilett
Journal: Br J Clin Pharmacol Date: 1990-01 Impact factor: 4.335

Excretion of oxazepam in breast milk.

1. Disposition of three benzodiazepines after single oral administration in man.

2. Benzodiazepine activity: is interaction with the glycine receptor, as evidenced by displacement of strychnine binding, a useful criterion?

3. Pharmacokinetics of oxazepam in healthy volunteers.

4. Determination of oxazepam in serum and urine by electron capture gas chromatography.

5. [Oxazepam withdrawal in the neonatal period].

6. Placental passage of oxazepam and its metabolism in mother and newborn.

7. An examination of acid-base equilibria of 1,4-benzodiazepines by spectrophotometry.

Review 8. Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations.

1. Excretion of temazepam in breast milk.

2. Excretion of diazepam and its metabolites in human milk during withdrawal from combination high dose diazepam and oxazepam.

3. Zolpidem excretion in breast milk.

Review 4. A guide to the safety of CNS-active agents during breastfeeding.

5. Pharmacokinetics in lactating women: prediction of alprazolam transfer into milk.

Review 6. Excretion of psychoactive drugs into breast milk. Pharmacokinetic principles and recommendations.

Review 7. Use of psychotropic medications in treating mood disorders during lactation : practical recommendations.

Review 8. Antidepressants, anxiolytics, and hypnotics in pregnancy and lactation.