Literature DB >> 3690801

Steroid receptors and human endometrial carcinoma: studies in a nude mouse model.

P G Satyaswaroop1, R J Zaino, R Mortel.   

Abstract

An experimental nude mouse system where human endometrial carcinomas of different histologic grade and steroid receptor characteristics can be grown and maintained under defined hormonal milieu by serial transplantation has been developed. Biologically and clinically important information on the role of steroid receptors in eliciting hormonal responses in these tumors has been obtained using this model. These results form the basis for designing and testing various treatment strategies for endometrial carcinomas of different histologic grade and receptor content.

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Year:  1987        PMID： 3690801     DOI： 10.1007/bf00144265

Source DB:  PubMed          Journal:  Cancer Metastasis Rev        ISSN： 0167-7659            Impact factor:   9.264


  31 in total

1.  Progestational agents in the treatment of carcinoma of the endometrium.

Authors:  R M KELLEY; W H BAKER
Journal:  N Engl J Med       Date:  1961-02-02       Impact factor: 91.245

2.  Treatment of advanced endometrial carcinoma with tamoxifen.

Authors:  K D Swenerton; G W White; D A Boyes
Journal:  N Engl J Med       Date:  1979-07-12       Impact factor: 91.245

3.  Female sex steroid receptors in postmenopausal endometrial carcinoma and biochemical response to an antiestrogen.

Authors:  R Mortel; C Levy; J P Wolff; J C Nicolas; P Robel; E E Baulieu
Journal:  Cancer Res       Date:  1981-03       Impact factor: 12.701

4.  Antagonism of development and growth of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors by the antiestrogen U 23,469 and effects on estrogen and progesterone receptors.

Authors:  T L Tsai; B S Katzenellenbogen
Journal:  Cancer Res       Date:  1977-05       Impact factor: 12.701

5.  Human endometrial adenocarcinoma transplanted into nude mice: growth regulation by estradiol.

Authors:  P G Satyaswaroop; R J Zaino; R Mortel
Journal:  Science       Date:  1983-01-07       Impact factor: 47.728

6.  Estrogen-like effects of tamoxifen on human endometrial carcinoma transplanted into nude mice.

Authors:  P G Satyaswaroop; R J Zaino; R Mortel
Journal:  Cancer Res       Date:  1984-09       Impact factor: 12.701

7.  Prolonged oestrogenic and mitogenic activity of tamoxifen in the ovariectomized mouse.

Authors:  L Martin; E Middleton
Journal:  J Endocrinol       Date:  1978-07       Impact factor: 4.286

8.  Association between steroid hormone receptors and response rate to cytotoxic chemotherapy in metastatic breast cancer.

Authors:  J C Allegra; M E Lippman; E B Thompson; R Simon; A Barlock; L Green; K K Huff; H M Do; S C Aitken; R Warren
Journal:  Cancer Treat Rep       Date:  1978-09

9.  Failure of progestins to induce estradiol dehydrogenase activity in endometrial carcinoma, in vitro.

Authors:  P G Satyaswaroop; R Mortel
Journal:  Cancer Res       Date:  1982-04       Impact factor: 12.701

10.  Estrogen and the growth of breast cancer: new evidence suggests indirect action.

Authors:  S M Shafie
Journal:  Science       Date:  1980-08-08       Impact factor: 47.728
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