Literature DB >> 3690577

Synthesis of heparin fragments: a methyl alpha-pentaoside with high affinity for antithrombin III.

M Petitou1, P Duchaussoy, I Lederman, J Choay, J C Jacquinet, P Sinaÿ, G Torri.   

Abstract

The synthesis is described of the methyl alpha-glycoside of the pentasaccharide which represents the sequence in heparin responsible for binding and activation of the anticoagulant protein Antithrombin III. It was obtained in a yield much better than that of the previously synthesised pentasaccharide and exhibited the same biological properties.

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Year:  1987        PMID: 3690577     DOI: 10.1016/0008-6215(87)80268-9

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  13 in total

Review 1.  The chemical neurobiology of carbohydrates.

Authors:  Heather E Murrey; Linda C Hsieh-Wilson
Journal:  Chem Rev       Date:  2008-05-02       Impact factor: 60.622

2.  Combinatorial one-pot chemoenzymatic synthesis of heparin.

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Journal:  Carbohydr Polym       Date:  2014-11-07       Impact factor: 9.381

3.  Facile chemoenzymatic synthesis of biotinylated heparosan hexasaccharide.

Authors:  Baolin Wu; Na Wei; Vireak Thon; Mohui Wei; Zaikuan Yu; Yongmei Xu; Xi Chen; Jian Liu; Peng George Wang; Tiehai Li
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4.  Chemical Sulfation of Small Molecules - Advances and Challenges.

Authors:  Rami A Al-Horani; Umesh R Desai
Journal:  Tetrahedron       Date:  2010-04-17       Impact factor: 2.457

Review 5.  Chemoenzymatic synthesis of the next generation of ultralow MW heparin therapeutics.

Authors:  Sayaka Masuko; Robert J Linhardt
Journal:  Future Med Chem       Date:  2012-03       Impact factor: 3.808

Review 6.  Engineering of routes to heparin and related polysaccharides.

Authors:  Ujjwal Bhaskar; Eric Sterner; Anne Marie Hickey; Akihiro Onishi; Fuming Zhang; Jonathan S Dordick; Robert J Linhardt
Journal:  Appl Microbiol Biotechnol       Date:  2011-11-03       Impact factor: 4.813

7.  Elimination of glycosylation heterogeneity affecting heparin affinity of recombinant human antithrombin III by expression of a beta-like variant in baculovirus-infected insect cells.

Authors:  E Ersdal-Badju; A Lu; X Peng; V Picard; P Zendehrouh; B Turk; I Björk; S T Olson; S C Bock
Journal:  Biochem J       Date:  1995-08-15       Impact factor: 3.857

Review 8.  The design and synthesis of new synthetic low-molecular-weight heparins.

Authors:  K Chandarajoti; J Liu; R Pawlinski
Journal:  J Thromb Haemost       Date:  2016-04-15       Impact factor: 5.824

9.  Comparative evaluation of efficacy, safety and haemostatic parameters of enoxaparin and fondaparinux in unstable coronary artery disease.

Authors:  Sanjay Shah; Vijay Khajuria; Vishal R Tandon; Zahid H Gillani; Mohan Lal
Journal:  J Clin Diagn Res       Date:  2014-01-12

Review 10.  Chemoenzymatic synthesis of heparan sulfate and heparin.

Authors:  Jian Liu; Robert J Linhardt
Journal:  Nat Prod Rep       Date:  2014-09-08       Impact factor: 13.423

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