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Literature DB >> 3690311

Subtle actions of 2-amino-4-phosphonobutyrate (APB) on the Off pathway in the mudpuppy retina.

Abstract

The principal action of 2-amino-4-phosphonobutyrate (APB) applied to the retina is the elimination of the On-bipolar cell light response. In this study, we report that APB also has more subtle effects; it sometimes enhances Off responses of Off bipolar cells and On, Off, and On-Off inner retina neurons. Possible mechanisms for this enhancement are considered.

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Year: 1987 PMID： 3690311 DOI： 10.1016/0006-8993(87)90433-1

Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252

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Cited

12 in total

1. The effect of 2-amino-4-phosphonobutyric acid on the oscillatory potentials of the electroretinogram.

Authors: P Guité; P Lachapelle
Journal: Doc Ophthalmol Date: 1990-09 Impact factor: 2.379

2. Analysis of the horizontal cell contribution to the receptive field surround of ganglion cells in the rabbit retina.

Authors: S C Mangel
Journal: J Physiol Date: 1991-10 Impact factor: 5.182

3. Feedforward lateral inhibition in retinal bipolar cells: input-output relation of the horizontal cell-depolarizing bipolar cell synapse.

Authors: X L Yang; S M Wu
Journal: Proc Natl Acad Sci U S A Date: 1991-04-15 Impact factor: 11.205

4. A Presynaptic Group III mGluR Recruits Gβγ/SNARE Interactions to Inhibit Synaptic Transmission by Cone Photoreceptors in the Vertebrate Retina.

Authors: Matthew J Van Hook; Norbert Babai; Zack Zurawski; Yun Young Yim; Heidi E Hamm; Wallace B Thoreson
Journal: J Neurosci Date: 2017-03-31 Impact factor: 6.167

10. Genetic disruption of the On visual pathway affects cortical orientation selectivity and contrast sensitivity in mice.

Authors: Rashmi Sarnaik; Hui Chen; Xiaorong Liu; Jianhua Cang
Journal: J Neurophysiol Date: 2014-03-05 Impact factor: 2.714

Subtle actions of 2-amino-4-phosphonobutyrate (APB) on the Off pathway in the mudpuppy retina.

1. The effect of 2-amino-4-phosphonobutyric acid on the oscillatory potentials of the electroretinogram.

2. Analysis of the horizontal cell contribution to the receptive field surround of ganglion cells in the rabbit retina.

3. Feedforward lateral inhibition in retinal bipolar cells: input-output relation of the horizontal cell-depolarizing bipolar cell synapse.

4. A Presynaptic Group III mGluR Recruits Gβγ/SNARE Interactions to Inhibit Synaptic Transmission by Cone Photoreceptors in the Vertebrate Retina.

5. Disinhibitory recruitment of NMDA receptor pathways in retina.

6. DL-2-amino-4-phosphonobutyric acid does not eliminate "ON" responses in the visual system of goldfish.

7. Intensity-dependent, rapid activation of presynaptic metabotropic glutamate receptors at a central synapse.

8. The "ON"-bipolar agonist, L-2-amino-4-phosphonobutyrate, blocks light-evoked cone contraction in xenopus eye cups.

9. Three distinct blue-green color pathways in a mammalian retina.

10. Genetic disruption of the On visual pathway affects cortical orientation selectivity and contrast sensitivity in mice.