Literature DB >> 3689355

Toxic effects of ozone on murine L929 fibroblasts. Damage to DNA.

J Van der Zee1, E Van Beek, T M Dubbelman, J Van Steveninck.   

Abstract

Damage to DNA caused by exposure of L929 fibroblasts to ozone was reflected by the generation of strand breaks, DNA inter-strand cross-links and DNA-protein cross-links. Addition of propan-2-ol, a hydroxyl radical scavenger, did not affect the formation of strand breaks. In model experiments it appeared that both purines and pyrimidines were involved in DNA inter-strand and DNA-protein cross-links.

Entities:  

Mesh:

Substances:

Year:  1987        PMID: 3689355      PMCID: PMC1148370          DOI: 10.1042/bj2470069

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  13 in total

1.  Ozonolysis of supercoiled pBR322 DNA resulting in strand scission to open circular DNA.

Authors:  K Sawadaishi; K Miura; E Ohtsuka; T Ueda; K Ishizaki; N Shinriki
Journal:  Nucleic Acids Res       Date:  1985-10-25       Impact factor: 16.971

2.  Site-specific and bulk-phase generation of hydroxyl radicals in the presence of cupric ions and thiol compounds.

Authors:  J van Steveninck; J van der Zee; T M Dubbelman
Journal:  Biochem J       Date:  1985-11-15       Impact factor: 3.857

3.  Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage.

Authors:  L Giloni; M Takeshita; F Johnson; C Iden; A P Grollman
Journal:  J Biol Chem       Date:  1981-08-25       Impact factor: 5.157

4.  Photodynamic effects of hematoporphyrin-derivative on transmembrane transport systems of murine L929 fibroblasts.

Authors:  T M Dubbelman; J Van Steveninck
Journal:  Biochim Biophys Acta       Date:  1984-04-11

5.  [DNA degradation and survival of ozone-resistant and -sensitive mutants isolated in Escherichia coli B (author's transl)].

Authors:  C Hamelin; Y S Chung
Journal:  Mol Gen Genet       Date:  1981

6.  Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation.

Authors:  H C Birnboim; J J Jevcak
Journal:  Cancer Res       Date:  1981-05       Impact factor: 12.701

7.  The role of hydroxyl radicals in the degradation of DNA by ozone.

Authors:  J Van der Zee; T M Dubbelman; J van Steveninck
Journal:  Free Radic Res Commun       Date:  1987

Review 8.  Ozone: an overview of its toxicity in man and animals.

Authors:  D B Menzel
Journal:  J Toxicol Environ Health       Date:  1984

9.  Copper salt-dependent hydroxyl radical formation. Damage to proteins acting as antioxidants.

Authors:  J M Gutteridge; S Wilkins
Journal:  Biochim Biophys Acta       Date:  1983-08-23

10.  Production of single- and double-strand breaks in plasmid DNA by ozone.

Authors:  C Hamelin
Journal:  Int J Radiat Oncol Biol Phys       Date:  1985-02       Impact factor: 7.038

View more
  1 in total

1.  DNA strand breaks in human nasal respiratory epithelium are induced upon exposure to urban pollution.

Authors:  L Calderon-Garciduenas; N Osnaya-Brizuela; L Ramirez-Martinez; A Villarreal-Calderon
Journal:  Environ Health Perspect       Date:  1996-02       Impact factor: 9.031

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.