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Literature DB >> 3687591

Roles of kallikrein-kinin system in acute inflammation: studies on high- and low-molecular weight kininogens-deficient rats (B/N-Katholiek strain).

S Oh-ishi¹, I Hayashi, I Utsunomiya, M Hayashi, K Yamaki, A Yamasu, T Nakano.

Abstract

Carrageenin-induced paw edema in HMW- and LMW-kininogens-deficient rats was significantly less than that in normal rats. There are three kininogens, HMW-, LMW- and T-kininogens, in normal rat plasma, but B/N-Katholiek rat plasma contains only T-kininogen. The pretreatment with captopril, a kiniase II inhibitor, enhanced paw swelling of normal rats, but not that of the deficient rats, indicating that bradykinin released from HMW-kininogen may have a role for the swelling but T-kinin may not be released in this inflammation.

Entities: Chemical Disease Species

Mesh：

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Year: 1987 PMID： 3687591 DOI： 10.1007/bf01966523

Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299

8 in total

1. Primary structures of the mRNAs encoding the rat precursors for bradykinin and T-kinin. Structural relationship of kininogens with major acute phase protein and alpha 1-cysteine proteinase inhibitor.

Authors: S Furuto-Kato; A Matsumoto; N Kitamura; S Nakanishi
Journal: J Biol Chem Date: 1985-10-05 Impact factor: 5.157

2. A radioimmunoassay for rat T-kininogen as an acute phase reactant.

Authors: I Hayashi; S Oh-ishi; K Enjyoji; H Kato; S Iwanaga
Journal: Chem Pharm Bull (Tokyo) Date: 1986-08 Impact factor: 1.645

3. Isolation and structure of T-kinin.

Authors: H Okamoto; L M Greenbaum
Journal: Biochem Biophys Res Commun Date: 1983-04-29 Impact factor: 3.575

4. Congenital deficiency in plasma kallikrein and kininogens in the brown Norway rat.

Authors: J Damas; A Adam
Journal: Experientia Date: 1980-05-15

5. Prolonged activated partial thromboplastin time and deficiency of high molecular weight kininogen in brown Norway rat mutant (Katholiek strain).

Authors: S Oh-ishi; I Hayashi; K Satoh; T Nakano
Journal: Thromb Res Date: 1984-02-15 Impact factor: 3.944

6. Evidence for a role of the plasma kallikrein-kinin system in acute inflammation: reduced exudation during carrageenin- and kaolin-pleurisies in kininogen-deficient rats.

Authors: S Oh-Ishi; I Hayashi; M Hayashi; K Yamaki; A Yamasu; T Nakano; I Utsunomiya; Y Nagashima
Journal: Agents Actions Date: 1986-06

7. Identification of T-kininogen in high and low molecular weight kininogens deficient rat (brown Norway Katholiek strain).

Authors: I Hayashi; S Oh-ishi; H Kato; K Enjyoji; S Iwanaga; T Nakano
Journal: Thromb Res Date: 1985-08-01 Impact factor: 3.944

8. The role of the kinin system in various inflammatory models in the rat.

Authors: J Damas; G Remacle-Volon; A Adam
Journal: Int J Tissue React Date: 1984

8 in total

6 in total

Review 6. A Novel Category of Anti-Hypertensive Drugs for Treating Salt-Sensitive Hypertension on the Basis of a New Development Concept.

Authors: Makoto Katori; Masataka Majima
Journal: Pharmaceuticals (Basel) Date: 2010-01-07

6 in total

Roles of kallikrein-kinin system in acute inflammation: studies on high- and low-molecular weight kininogens-deficient rats (B/N-Katholiek strain).

1. Primary structures of the mRNAs encoding the rat precursors for bradykinin and T-kinin. Structural relationship of kininogens with major acute phase protein and alpha 1-cysteine proteinase inhibitor.

2. A radioimmunoassay for rat T-kininogen as an acute phase reactant.

3. Isolation and structure of T-kinin.

4. Congenital deficiency in plasma kallikrein and kininogens in the brown Norway rat.

5. Prolonged activated partial thromboplastin time and deficiency of high molecular weight kininogen in brown Norway rat mutant (Katholiek strain).

6. Evidence for a role of the plasma kallikrein-kinin system in acute inflammation: reduced exudation during carrageenin- and kaolin-pleurisies in kininogen-deficient rats.

7. Identification of T-kininogen in high and low molecular weight kininogens deficient rat (brown Norway Katholiek strain).

8. The role of the kinin system in various inflammatory models in the rat.

1. Reduction of sodium deoxycholic acid-induced scratching behaviour by bradykinin B2 receptor antagonists.

2. Pro-inflammatory properties of the kallikrein-kinin system: potential for new drug therapy.

3. Kinins and peritoneal exudates induced by carrageenin and zymosan in rats.

4. Comparative study of endotoxin-induced hypotension in kininogen-deficient rats with that in normal rats.

5. Presence of T-kininogen and kinins in sponge-induced exudates in rats.

Review 6. A Novel Category of Anti-Hypertensive Drugs for Treating Salt-Sensitive Hypertension on the Basis of a New Development Concept.