Literature DB >> 3687373

Linoleic acid levels in white blood cells, platelets, and serum of multiple sclerosis patients.

M Fisher1, M H Johnson, A M Natale, P H Levine.   

Abstract

We found a small but statistically significant reduction in the linoleic acid concentration of white blood cells and platelets in MS patients. The percent linoleic acid concentration (mean +/- S.D.) in the white blood cells if 24 MS patients was 8.8 +/- 1.8% as compared with 11.4 +/- 4.9 in 24 age and sex-matched controls (p less than 0.05). Platelet levels were 8.5 +/- 2.4% and 10.6 +/- 3.8% respectively (P less than 0.05). Serum linoleic acid levels were not significantly different in the two groups. The possible role of linoleic acid in the pathogenesis of MS has yet to be defined.

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Year:  1987        PMID: 3687373     DOI: 10.1111/j.1600-0404.1987.tb03574.x

Source DB:  PubMed          Journal:  Acta Neurol Scand        ISSN: 0001-6314            Impact factor:   3.209


  6 in total

1.  Monounsaturated fatty acids in blood cell membranes from patients with multiple sclerosis.

Authors:  Gloudina Maria Hon; Mogamat Shafick Hassan; Susan Janse van Rensburg; Stefan Abel; Rajiv T Erasmus; Tandi Matsha
Journal:  Inflammation       Date:  2011-12       Impact factor: 4.092

Review 2.  [Diet and multiple sclerosis].

Authors:  S Schwarz; H Leweling
Journal:  Nervenarzt       Date:  2005-02       Impact factor: 1.214

3.  The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-beta1) up-regulation and increased prostaglandin E2 (PGE2) production.

Authors:  L S Harbige; L Layward; M M Morris-Downes; D C Dumonde; S Amor
Journal:  Clin Exp Immunol       Date:  2000-12       Impact factor: 4.330

4.  Omega-3 fatty acids and multiple sclerosis: relationship to depression.

Authors:  Robin L Aupperle; Douglas R Denney; Sharon G Lynch; Susan E Carlson; Debra K Sullivan
Journal:  J Behav Med       Date:  2008-04

Review 5.  Polyunsaturated fatty acids and their potential therapeutic role in multiple sclerosis.

Authors:  Lahar R Mehta; Robert H Dworkin; Steven R Schwid
Journal:  Nat Clin Pract Neurol       Date:  2009-02

6.  Multiple Sclerosis: Immunotherapy.

Authors: 
Journal:  Curr Treat Options Neurol       Date:  1999-07       Impact factor: 3.972

  6 in total

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