| Literature DB >> 3680490 |
M De Almeida1, M Herry, J Testart, J Belaisch-Allart, R Frydman, P Jouannet.
Abstract
Thirteen infertile women with high titres of spermagglutinating antibodies in their serum and/or in cervical mucus underwent in-vitro fertilization (IVF) and embryo transfer (ET). Fertilization occurred in 68% of the oocytes in a serum-free medium. Eight pregnancies were obtained in 22 IVF cycles (36.4%). Anti-sperm antibodies were found in the follicular fluids of 5 out of the 11 women with circulating antibodies. Fertilization results were independent of both the localization and the level of anti-sperm antibodies. From these data we can conclude that IVF-ET is a suitable treatment for long lasting female infertility linked to anti-sperm immunity.Entities:
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Year: 1987 PMID: 3680490 DOI: 10.1093/oxfordjournals.humrep.a136596
Source DB: PubMed Journal: Hum Reprod ISSN: 0268-1161 Impact factor: 6.918