Literature DB >> 3677994

Alternative splicing increases the diversity of the human protein kinase C family.

L Coussens1, L Rhee, P J Parker, A Ullrich.   

Abstract

Isolation of two protein kinase C (PKC) cDNA clones containing divergent carboxy-terminal sequences suggested a common genetic origin for these cDNAs. Partial characterization of the hPKC beta chromosomal gene provided direct evidence for the existence of two adjacent carboxy-terminal exons (beta 1 and beta 2) that are alternatively spliced to generate two types of hPKC beta sequences. PKC beta 1 and beta 2 mRNAs are expressed in a selective manner in both human hematopoietic cells and bovine brain tissues.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3677994     DOI： 10.1089/dna.1987.6.389

Source DB:  PubMed          Journal:  DNA        ISSN： 0198-0238


  15 in total

Review 1.  Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis.

Authors:  B L Webb; S J Hirst; M A Giembycz
Journal:  Br J Pharmacol       Date:  2000-08       Impact factor: 8.739

2.  Differential effects of PKA-controlled CaMKK2 variants on neuronal differentiation.

Authors:  Wenguang Cao; Muhammad Sohail; Guodong Liu; Geremy A Koumbadinga; Vincent G Lobo; Jiuyong Xie
Journal:  RNA Biol       Date:  2011-11-01       Impact factor: 4.652

Review 3.  Specific protein kinase C isoforms as transducers and modulators of insulin signaling.

Authors:  Sanford R Sampson; Denise R Cooper
Journal:  Mol Genet Metab       Date:  2006-06-23       Impact factor: 4.797

Review 4.  The extended protein kinase C superfamily.

Authors:  H Mellor; P J Parker
Journal:  Biochem J       Date:  1998-06-01       Impact factor: 3.857

5.  A sequence compilation and comparison of exons that are alternatively spliced in neurons.

Authors:  S Stamm; M Q Zhang; T G Marr; D M Helfman
Journal:  Nucleic Acids Res       Date:  1994-05-11       Impact factor: 16.971

Review 6.  Protein kinase C isoenzymes: divergence in signal transduction?

Authors:  H Hug; T F Sarre
Journal:  Biochem J       Date:  1993-04-15       Impact factor: 3.857

7.  Acute ethanol exposure prevents PMA-mediated augmentation of N-methyl-D-aspartate receptor function in primary cultured cerebellar granule cells.

Authors:  Jason Reneau; Mary E Reyland; R Lisa Popp
Journal:  Alcohol       Date:  2011-05-31       Impact factor: 2.405

8.  Altered expression of protein kinase C, lck, and CD45 in a 12-O-tetradecanoylphorbol-13-acetate-dependent leukemic T-cell variant that expresses a high level of interleukin-2 receptor.

Authors:  K M Tchou-Wong; I B Weinstein
Journal:  Mol Cell Biol       Date:  1992-01       Impact factor: 4.272

9.  Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart.

Authors:  N Bacher; Y Zisman; E Berent; E Livneh
Journal:  Mol Cell Biol       Date:  1991-01       Impact factor: 4.272

10.  Protein kinase C beta expression in melanoma cells and melanocytes: differential expression correlates with biological responses to 12-O-tetradecanoylphorbol 13-acetate.

Authors:  M B Powell; R K Rosenberg; M J Graham; M L Birch; D T Yamanishi; J A Buckmeier; F L Meyskens
Journal:  J Cancer Res Clin Oncol       Date:  1993       Impact factor: 4.553
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.