Literature DB >> 3677612

Comparison of ornithine aminotransferase activities in the pigment epithelium and retina of vertebrates.

K Ratzlaff1, A Baich.   

Abstract

1. The specific activities of ornithine aminotransferase (OAT) in the pigment epithelia, retinas, and livers from several classes of vertebrates were assayed. 2. The specific activities of OAT were much higher in the pigment epithelia from mammals and birds than in their respective retinas or livers. 3. Pigment epithelium from porcine eyes had the highest specific activity measured. The specific activity of OAT in the pigment epithelium from the pig was five times higher than the OAT activity in its retina and 13 times higher than the OAT activity in its liver.

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Year:  1987        PMID: 3677612     DOI: 10.1016/0305-0491(87)90075-7

Source DB:  PubMed          Journal:  Comp Biochem Physiol B        ISSN: 0305-0491


  5 in total

1.  Correction of ornithine accumulation prevents retinal degeneration in a mouse model of gyrate atrophy of the choroid and retina.

Authors:  T Wang; G Steel; A H Milam; D Valle
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-01       Impact factor: 11.205

2.  A mouse model of gyrate atrophy of the choroid and retina. Early retinal pigment epithelium damage and progressive retinal degeneration.

Authors:  T Wang; A H Milam; G Steel; D Valle
Journal:  J Clin Invest       Date:  1996-06-15       Impact factor: 14.808

3.  Gyrate atrophy: clinical and genetic findings in a female without arginine-restricted diet during her first 39 years of life and report of a new OAT gene mutation.

Authors:  Agnes B Renner; Andreas Walter; Britta S Fiebig; Herbert Jägle
Journal:  Doc Ophthalmol       Date:  2012-06-07       Impact factor: 2.379

Review 4.  Ornithine Aminotransferase, an Important Glutamate-Metabolizing Enzyme at the Crossroads of Multiple Metabolic Pathways.

Authors:  Antonin Ginguay; Luc Cynober; Emmanuel Curis; Ioannis Nicolis
Journal:  Biology (Basel)       Date:  2017-03-07

5.  Partial regression of foveoschisis following vitamin B6 supplementary therapy for gyrate atrophy in a Chinese girl.

Authors:  Wenxue Guan; Ge Wang; Feng Hu; Xiaoyan Peng
Journal:  BMC Ophthalmol       Date:  2021-02-18       Impact factor: 2.209

  5 in total

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