| Literature DB >> 3677063 |
B K Nielsen1, L U Thompson, R P Bird.
Abstract
Cell proliferation was studied in descending, transverse and ascending colonic crypts of rats fed either 0%, 0.6%, 1.2% or 2.0% phytic acid (PA). Significant effects of phytic acid were seen only in the descending colon. No changes in crypt height were observed. Both the 1.2 and 2.0% phytic acid groups exhibited significantly lower uppermost labelled cells than the control group. Animals given 1.2% and 2.0% phytic acid also showed significantly reduced DNA synthetic cells, as indicated by lower labelling indices.Entities:
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Year: 1987 PMID： 3677063 DOI： 10.1016/0304-3835(87)90117-0
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679