Literature DB >> 3676769

Angiotensin receptor binding in human hypothalamus: autoradiographic localization.

M J McKinley1, A M Allen, J Clevers, G Paxinos, F A Mendelsohn.   

Abstract

Binding of 125I-[Sar1,Ile8]angiotensin II in the human hypothalamus was mapped by in vitro autoradiography carried out on frozen sections of hypothalamus from two human brains. Regions showing the greatest specific binding of this radioligand were the organum vasculosum of the lamina terminalis, median preoptic nucleus, subfornical organ, median eminence, arcuate nucleus and paraventricular nucleus. These regions may be sites of angiotensin II receptors involved in the regulation of blood pressure, fluid balance and pituitary hormone secretion.

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Year:  1987        PMID： 3676769     DOI： 10.1016/0006-8993(87)91260-1

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  8 in total

1.  Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism.

Authors:  Kristin E Claflin; Jeremy A Sandgren; Allyn M Lambertz; Benjamin J Weidemann; Nicole K Littlejohn; Colin M L Burnett; Nicole A Pearson; Donald A Morgan; Katherine N Gibson-Corley; Kamal Rahmouni; Justin L Grobe
Journal:  J Clin Invest       Date:  2017-03-06       Impact factor: 14.808

Review 2.  Control of energy balance by the brain renin-angiotensin system.

Authors:  Kristin E Claflin; Justin L Grobe
Journal:  Curr Hypertens Rep       Date:  2015-05       Impact factor: 5.369

3.  Angiotensin AT1A receptors expressed in vasopressin-producing cells of the supraoptic nucleus contribute to osmotic control of vasopressin.

Authors:  Jeremy A Sandgren; Danny W Linggonegoro; Shao Yang Zhang; Sarah A Sapouckey; Kristin E Claflin; Nicole A Pearson; Mariah R Leidinger; Gary L Pierce; Mark K Santillan; Katherine N Gibson-Corley; Curt D Sigmund; Justin L Grobe
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2018-01-24       Impact factor: 3.619

4.  A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity.

Authors:  Aline M Hilzendeger; Donald A Morgan; Leonard Brooks; David Dellsperger; Xuebo Liu; Justin L Grobe; Kamal Rahmouni; Curt D Sigmund; Allyn L Mark
Journal:  Am J Physiol Heart Circ Physiol       Date:  2012-05-18       Impact factor: 4.733

5.  Increased (pro)renin receptor expression in the subfornical organ of hypertensive humans.

Authors:  Silvana G Cooper; Darshan P Trivedi; Rieko Yamamoto; Caleb J Worker; Cheng-Yuan Feng; Jacob T Sorensen; Wei Yang; Zhenggang Xiong; Yumei Feng
Journal:  Am J Physiol Heart Circ Physiol       Date:  2017-12-22       Impact factor: 4.733

6.  Angiotensin type 1a receptors in the forebrain subfornical organ facilitate leptin-induced weight loss through brown adipose tissue thermogenesis.

Authors:  Colin N Young; Donald A Morgan; Scott D Butler; Kamal Rahmouni; Susan B Gurley; Thomas M Coffman; Allyn L Mark; Robin L Davisson
Journal:  Mol Metab       Date:  2015-01-31       Impact factor: 7.422

Review 7.  ACE2, Circumventricular Organs and the Hypothalamus, and COVID-19.

Authors:  Wei-Yi Ong; R L Satish; Deron R Herr
Journal:  Neuromolecular Med       Date:  2022-04-22       Impact factor: 4.103

Review 8.  The Arcuate Nucleus of the Hypothalamus and Metabolic Regulation: An Emerging Role for Renin-Angiotensin Pathways.

Authors:  Darren Mehay; Yuval Silberman; Amy C Arnold
Journal:  Int J Mol Sci       Date:  2021-06-30       Impact factor: 5.923
  8 in total

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