Literature DB >> 3676752

Dose-dependent antinociceptive action of neurotensin microinjected into the rostroventromedial medulla of the rat.

F G Fang1, J L Moreau, H L Fields.   

Abstract

Microinjection of neurotensin into the rat rostroventromedial medulla produces dose-dependent inhibition of the tailflick reflex (ED50 of 2.06 nmol/animal (1.33-3.19)). The peak effect occurs 15-20 min following injection and, at the highest dose used, lasts up to 70 min.

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Year:  1987        PMID： 3676752     DOI： 10.1016/0006-8993(87)90255-1

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  7 in total

1.  Systemically and topically active antinociceptive neurotensin compounds.

Authors:  Grace C Rossi; Joshua E Matulonis; Elliott Richelson; Denise Barbut; Gavril W Pasternak
Journal:  J Pharmacol Exp Ther       Date:  2010-06-24       Impact factor: 4.030

2.  Antinociceptive role of neurotensin receptor 1 in rats with chemotherapy-induced peripheral neuropathy.

Authors:  Mei Yin; Yeo-Ok Kim; Jeong-Il Choi; Seongtae Jeong; Si-Ho Yang; Hong-Beom Bae; Myung-Ha Yoon
Journal:  Korean J Pain       Date:  2020-10-01

3.  Neurochemical properties of BDNF-containing neurons projecting to rostral ventromedial medulla in the ventrolateral periaqueductal gray.

Authors:  Jun-Bin Yin; Huang-Hui Wu; Yu-Lin Dong; Ting Zhang; Jian Wang; Yong Zhang; Yan-Yan Wei; Ya-Cheng Lu; Sheng-Xi Wu; Wen Wang; Yun-Qing Li
Journal:  Front Neural Circuits       Date:  2014-11-20       Impact factor: 3.492

Review 4.  To ingest or rest? Specialized roles of lateral hypothalamic area neurons in coordinating energy balance.

Authors:  Juliette A Brown; Hillary L Woodworth; Gina M Leinninger
Journal:  Front Syst Neurosci       Date:  2015-02-18

5.  Systemically administered neurotensin receptor agonist produces antinociception through activation of spinally projecting serotonergic neurons in the rostral ventromedial medulla.

Authors:  Yaqun Li; Dong Ho Kang; Woong Mo Kim; Hyung Gon Lee; Seung Hoon Kim; Hyun Eung You; Jeong Il Choi; Myung Ha Yoon
Journal:  Korean J Pain       Date:  2021-01-01

6.  Diverse roles of neurotensin agonists in the central nervous system.

Authors:  Mona Boules; Zhimin Li; Kristin Smith; Paul Fredrickson; Elliott Richelson
Journal:  Front Endocrinol (Lausanne)       Date:  2013-03-22       Impact factor: 5.555

7.  Neurotensin-produced antinociception in the rostral ventromedial medulla is partially mediated by spinal cord norepinephrine.

Authors:  A V Buhler; H K Proudfit; G F Gebhart
Journal:  Pain       Date:  2007-07-30       Impact factor: 7.926
  7 in total

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