Literature DB >> 3676312

The mechanism of liposomal damage by taurocholate.

P Walde1, J Sunamoto, C J O'Connor.   

Abstract

The stability of small unilamellar vesicles formed by egg-yolk phosphatidylcholine (PC) has been examined in the presence of sodium taurocholate. The permeability of the vesicular membrane changes as the total taurocholate concentration increases, until a transformation from mixed bile salt/PC vesicles to mixed micelles occurs. Based on experiments in which the bile salt-induced release of either hydrophilic (carboxyfluorescein) or hydrophobic (Bromothymol blue) probes was studied, and on fluorescence polarization of the probe 1,6-diphenyl-1,3,5-hexatriene and turbidity measurements, a two-step process for the initial stage of liposomal damage by taurocholate is postulated.

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Year:  1987        PMID： 3676312     DOI： 10.1016/0005-2736(87)90005-8

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  9 in total

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Journal:  Nanotechnol Rev       Date:  2017-12-12       Impact factor: 7.848

2.  Interactions between organic anions, micelles and vesicles in model bile systems.

Authors:  H J Verkade; M A de Bruijn; M A Brink; H Talsma; R J Vonk; F Kuipers; A K Groen
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3.  Insertion and partition of sodium taurocholate into egg phosphatidylcholine vesicles.

Authors:  Karine Andrieux; Laura Forte; Sylviane Lesieur; Maité Paternostre; Michel Ollivon; Cécile Grabielle-Madelmont
Journal:  Pharm Res       Date:  2004-08       Impact factor: 4.200

4.  Optimization on condition of epigallocatechin-3-gallate (EGCG) nanoliposomes by response surface methodology and cellular uptake studies in Caco-2 cells.

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5.  Optimization of Conditions for Cyanidin-3-OGlucoside (C3G) Nanoliposome Production by Response Surface Methodology and Cellular Uptake Studies in Caco-2 Cells.

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Journal:  Molecules       Date:  2017-03-13       Impact factor: 4.411

6.  Bolalipid-Doped Liposomes: Can Bolalipids Increase the Integrity of Liposomes Exposed to Gastrointestinal Fluids?

Authors:  Sindy Müller; Kai Gruhle; Annette Meister; Gerd Hause; Simon Drescher
Journal:  Pharmaceutics       Date:  2019-12-03       Impact factor: 6.321

7.  Liposome leakage and increased cellular permeability induced by guanidine-based oligomers: effects of liposome composition on liposome leakage and human lung epithelial barrier permeability.

Authors:  Yeonjeong Ha; Yerim Koo; Seon-Kyung Park; Ga-Eun Kim; Han Bin Oh; Ha Ryong Kim; Jung-Hwan Kwon
Journal:  RSC Adv       Date:  2021-09-28       Impact factor: 4.036

8.  Development and characterization of lactoferrin nanoliposome: cellular uptake and stability.

Authors:  Rongfa Guan; Jieqing Ma; Yihang Wu; Fei Lu; Chaogeng Xiao; Han Jiang; Tianshu Kang
Journal:  Nanoscale Res Lett       Date:  2012-12-17       Impact factor: 4.703

9.  Cefotaxime pharmacokinetics after oral application in the form of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate microvesicles in rat.

Authors:  Svetlana Golocorbin-Kon; Momir Mikov; Mousab Arafat; Zika Lepojevic; Ivan Mikov; Majda Sahman-Zaimovic; Zdenko Tomic
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2009 Jan-Mar       Impact factor: 2.569
  9 in total

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