Literature DB >> 3674837

[Eremomycin--a new antibiotic from the cyclic glycopeptide group].

G F Gauze, M G Brazhnikova, A V Laĭko, M A Sveshnikova, T P Preobrazhenskaia.   

Abstract

Eremomycin, a novel antibiotic belonging to the group of cyclic glycopeptides is produced by an actinomycete designated INA-238. Biosynthesis, isolation, physico-chemical and biological properties of the antibiotic are described. Eremomycin is shown to be close to vancomycin. However, by its chromatographic and electrophoretic mobility, presence of chlorine in the antibiotic molecule and optic characteristics eremomycin differs from vancomycin. Eremomycin is less toxic than vancomycin whereas its chemotherapeutic activity in treatment of infections caused by gram-positive organisms is higher.

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Year:  1987        PMID: 3674837

Source DB:  PubMed          Journal:  Antibiot Med Biotekhnol        ISSN: 0233-7525


  1 in total

1.  Evaluation of Toxic Properties of New Glycopeptide Flavancin on Rats.

Authors:  Michael I Treshchalin; Vasilisa A Polozkova; Elena I Moiseenko; Helen M Treshalina; Andrey E Shchekotikhin; Eleonora R Pereverzeva
Journal:  Pharmaceuticals (Basel)       Date:  2022-05-25
  1 in total

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