| Literature DB >> 3674394 |
M P Thomas1, G Patonay, I M Warner.
Abstract
Multidimensional fluorescence-detected circular dichroism (FDCD) is used to investigate the binding of bilirubin to four mammalian serum albumins. It is shown that the complexes formed with the albumins have distinctly different FDCD spectra. The effect of the pH-dependent transition from basic to acidic conditions on the complexes is examined. The binding of warfarin to albumin is also presented to demonstrate the general analytical utility of the multidimensional FDCD measurement for biochemical analysis.Entities:
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Year: 1987 PMID： 3674394 DOI： 10.1016/0003-2697(87)90520-3
Source DB: PubMed Journal: Anal Biochem ISSN： 0003-2697 Impact factor: 3.365