Literature DB >> 3673329

A comparison of live and formalised leptospiral microscopic agglutination test.

M F Palmer1, S A Waitkins, S W Wanyangu.   

Abstract

The sensitivity and reliability of a formalised leptospiral antigen battery was compared with a smaller battery of live leptospiral antigens with 152 human sera positive for leptospirosis. There was good concurrence of results between the formalised and live antigens, however the live battery did fail to detect some positive sera where the antibody level was low. The formalised antigens were more sensitive than the live (P less than 0.001) and more reliable in the detection of early leptospiral infection, but the live antigens were more specific in the determination of probable infecting serogroup.

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Year:  1987        PMID: 3673329     DOI: 10.1016/s0176-6724(87)80161-x

Source DB:  PubMed          Journal:  Zentralbl Bakteriol Mikrobiol Hyg A        ISSN: 0176-6724


  3 in total

Review 1.  Leptospirosis.

Authors:  P N Levett
Journal:  Clin Microbiol Rev       Date:  2001-04       Impact factor: 26.132

2.  An evaluation of three commercial kits for use as screening methods for the detection of leptospiral antibodies in the UK.

Authors:  W J Zochowski; M F Palmer; T J Coleman
Journal:  J Clin Pathol       Date:  2001-01       Impact factor: 3.411

3.  Effect of heat or formalin treatment of leptospires on antibody response detected by immunoblotting.

Authors:  V Pope; R C Johnson
Journal:  J Clin Microbiol       Date:  1991-07       Impact factor: 5.948

  3 in total

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