Literature DB >> 36686

Efficacy of pro-PAM (N-methyl-1,6-dihydropyridine-2-carbaldoxime hydrochloride) as a prophylaxis against organophosphate poisoning.

J G Clement.   

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Year:  1979        PMID： 36686     DOI： 10.1016/0041-008x(79)90325-9

Source DB:  PubMed          Journal:  Toxicol Appl Pharmacol        ISSN： 0041-008X            Impact factor:   4.219


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  10 in total

1.  In vitro oxime-induced reactivation of various molecular forms of soman-inhibited acetylcholinesterase in striated muscle from rat, monkey and human.

Authors:  J G Clement; N Erhardt
Journal:  Arch Toxicol       Date:  1994       Impact factor: 5.153

2.  Novel brain-penetrating oximes for reactivation of cholinesterase inhibited by sarin and VX surrogates.

Authors:  Janice E Chambers; Edward C Meek; Howard W Chambers
Journal:  Ann N Y Acad Sci       Date:  2016-05-06       Impact factor: 5.691

3.  Efficacy of a combination of acetylcholinesterase reactivators, HI-6 and obidoxime, against tabun and soman poisoning of mice.

Authors:  J G Clement; J D Shiloff; C Gennings
Journal:  Arch Toxicol       Date:  1987       Impact factor: 5.153

4.  In vitro P-glycoprotein activity does not completely explain in vivo efficacy of novel centrally effective oxime acetylcholinesterase reactivators.

Authors:  Mary Beth Dail; Edward Caldwell Meek; Howard Wayne Chambers; Janice Elaine Chambers
Journal:  Drug Chem Toxicol       Date:  2018-05-03       Impact factor: 3.356

5.  Effect of calcium antagonists (omega-conotoxin GVIA, verapamil, gallopamil, diltiazem) on bronchial smooth muscle contractions induced by soman.

Authors:  P Walday; E Fyllingen; P Aas
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1992-09       Impact factor: 3.000

6.  Comparison of several oximes on reactivation of soman-inhibited blood, brain and tissue cholinesterase activity in rats.

Authors:  T M Shih
Journal:  Arch Toxicol       Date:  1993       Impact factor: 5.153

7.  Novel substituted phenoxyalkyl pyridinium oximes enhance survival and attenuate seizure-like behavior of rats receiving lethal levels of nerve agent surrogates.

Authors:  Janice E Chambers; Edward C Meek; Joshua P Bennett; W Shane Bennett; Howard W Chambers; C Andrew Leach; Ronald B Pringle; Robert W Wills
Journal:  Toxicology       Date:  2015-12-17       Impact factor: 4.221

Review 8.  Oxime-mediated reactivation of organophosphate-inhibited acetylcholinesterase with emphasis on centrally-active oximes.

Authors:  Janice E Chambers; Mary B Dail; Edward C Meek
Journal:  Neuropharmacology       Date:  2020-06-13       Impact factor: 5.250

9.  An efficient in vitro assay for acetylcholinesterase reactivators using immobilized enzyme.

Authors:  A M Trammel; J E Simmons; R T Borchardt
Journal:  Pharm Res       Date:  1984-05       Impact factor: 4.200

10.  Use of the 2-Pyridinealdoxime/N,N'-Donor Ligand Combination in Cobalt(III) Chemistry: Synthesis and Characterization of Two Cationic Mononuclear Cobalt(III) Complexes.

Authors:  Konstantis F Konidaris; Catherine P Raptopoulou; Vassilis Psycharis; Spyros P Perlepes; Evy Manessi-Zoupa; Theocharis C Stamatatos
Journal:  Bioinorg Chem Appl       Date:  2010-07-18       Impact factor: 7.778
  10 in total

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