| Literature DB >> 3668531 |
K D Haegele1, J J Schwartz, J Schoun, A H Schmitt, P J Schechter.
Abstract
2-Pyrrolidinone, the lactam of gamma-aminobutyric acid (GABA), is identified as the major constituent of total GABA in human CSF. Structural elucidation was done by mass spectrometry. In lumbar CSF of four patients, 2-pyrrolidinone represented about 54% of GABA found after acid hydrolysis, thus accounting for essentially all of the hitherto unknown GABA fraction in CSF.Entities:
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Year: 1987 PMID： 3668531 DOI： 10.1111/j.1471-4159.1987.tb01006.x
Source DB: PubMed Journal: J Neurochem ISSN： 0022-3042 Impact factor: 5.372