| Literature DB >> 3667778 |
G A Kyerematen1, L H Taylor, J D deBethizy, E S Vesell.
Abstract
A sensitive, reproducible radiometric-high-performance liquid chromatographic assay has been developed to measure concentrations of nicotine and twelve of its metabolites in biological fluids. Following administration of nicotine ([2-14C]pyrrolidine) to rats, the assay was used in a pharmacokinetic investigation.Entities:
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Year: 1987 PMID: 3667778 DOI: 10.1016/0378-4347(87)80277-3
Source DB: PubMed Journal: J Chromatogr