Literature DB >> 3667778

Radiometric-high-performance liquid chromatographic assay for nicotine and twelve of its metabolites.

G A Kyerematen1, L H Taylor, J D deBethizy, E S Vesell.   

Abstract

A sensitive, reproducible radiometric-high-performance liquid chromatographic assay has been developed to measure concentrations of nicotine and twelve of its metabolites in biological fluids. Following administration of nicotine ([2-14C]pyrrolidine) to rats, the assay was used in a pharmacokinetic investigation.

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Year:  1987        PMID: 3667778     DOI: 10.1016/0378-4347(87)80277-3

Source DB:  PubMed          Journal:  J Chromatogr


  1 in total

1.  Influence of nicotine on tissue trace element concentrations and tissue antioxidant defense.

Authors:  M A Dubick; C L Keen
Journal:  Biol Trace Elem Res       Date:  1991-11       Impact factor: 3.738

  1 in total

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