| Literature DB >> 3667170 |
T L Richards1, F Terrier, R E Sievers, M J Lipton, M E Moseley, C B Higgins.
Abstract
Proton magnetic resonance (MR) spectroscopy with homonuclear editing was used to assess lactate accumulation in ischemic and anoxic hearts perfused according to the Langendorff method. An increase in the lactate signal was observed after 5 minutes of ischemia and after 10 to 20 minutes of anoxia. This study demonstrates that proton MR spectroscopy can be used to monitor the time course of MR-visible lactate levels in ischemic and anoxic isolated rat hearts.Entities:
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Year: 1987 PMID： 3667170 DOI： 10.1097/00004424-198708000-00004
Source DB: PubMed Journal: Invest Radiol ISSN： 0020-9996 Impact factor: 6.016