Literature DB >> 3666131

Differential regulation of muscle acetylcholine receptor gamma- and epsilon-subunit mRNAs.

V Witzemann1, B Barg, Y Nishikawa, B Sakmann, S Numa.   

Abstract

The contents of the mRNAs encoding the gamma- and epsilon-subunits of the nicotinic acetylcholine receptor as well as the single-channel properties of the receptor have been assessed in innervated, denervated and reinnervated rat muscle. The changes in abundance of the gamma- and epsilon-subunit mRNAs correlate with the changes in relative density of two classes of acetylcholine receptor channels. The results support the view that a switch in the relative abundance of the gamma- and epsilon-subunit mRNAs is a major mechanism in regulating the properties of acetylcholine receptor channels in muscle.

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Year:  1987        PMID： 3666131     DOI： 10.1016/0014-5793(87)80518-5

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  47 in total

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Authors:  S Gattenloehner; B Dockhorn-Dworniczak; I Leuschner; A Vincent; H K Müller-Hermelink; A Marx
Journal:  J Mol Diagn       Date:  1999-11       Impact factor: 5.568

2.  Turnover of acetylcholine receptors at the endplate revisited: novel insights into nerve-dependent behavior.

Authors:  Siegfried Strack; Muzamil Majid Khan; Franziska Wild; Anika Rall; Rüdiger Rudolf
Journal:  J Muscle Res Cell Motil       Date:  2015-08-15       Impact factor: 2.698

3.  Prolongation of evoked and spontaneous synaptic currents at the neuromuscular junction after activity blockade is caused by the upregulation of fetal acetylcholine receptors.

Authors:  Xueyong Wang; Kathrin L Engisch; Russell W Teichert; Baldomero M Olivera; Martin J Pinter; Mark M Rich
Journal:  J Neurosci       Date:  2006-08-30       Impact factor: 6.167

4.  A uniquely selective inhibitor of the mammalian fetal neuromuscular nicotinic acetylcholine receptor.

Authors:  Russell W Teichert; Jean Rivier; Josep Torres; John Dykert; Charleen Miller; Baldomero M Olivera
Journal:  J Neurosci       Date:  2005-01-19       Impact factor: 6.167

Review 5.  Ligand-gated ion channels. Homology and diversity.

Authors:  V B Cockcroft; D J Osguthorpe; E A Barnard; A E Friday; G G Lunt
Journal:  Mol Neurobiol       Date:  1990 Fall-Winter       Impact factor: 5.590

6.  Spontaneous and agonist-induced openings of an acetylcholine receptor channel composed of bovine muscle alpha-, beta- and delta-subunits.

Authors:  M B Jackson; K Imoto; M Mishina; T Konno; S Numa; B Sakmann
Journal:  Pflugers Arch       Date:  1990-10       Impact factor: 3.657

7.  Increased expression of dystrophin, beta-dystroglycan and adhalin in denervated rat muscles.

Authors:  D Biral; L Senter; G Salviati
Journal:  J Muscle Res Cell Motil       Date:  1996-10       Impact factor: 2.698

8.  A novel synapse-associated noncoding RNA.

Authors:  M A Velleca; M C Wallace; J P Merlie
Journal:  Mol Cell Biol       Date:  1994-11       Impact factor: 4.272

9.  Depressed Synaptic Transmission and Reduced Vesicle Release Sites in Huntington's Disease Neuromuscular Junctions.

Authors:  Ahmad Khedraki; Eric J Reed; Shannon H Romer; Qingbo Wang; William Romine; Mark M Rich; Robert J Talmadge; Andrew A Voss
Journal:  J Neurosci       Date:  2017-07-19       Impact factor: 6.167

10.  NCAM(CD56) and RUNX1(AML1) are up-regulated in human ischemic cardiomyopathy and a rat model of chronic cardiac ischemia.

Authors:  Stefan Gattenlöhner; Christiane Waller; Georg Ertl; Burkhard-Dieter Bültmann; Hans-Konrad Müller-Hermelink; Alexander Marx
Journal:  Am J Pathol       Date:  2003-09       Impact factor: 4.307
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