Literature DB >> 366342

Estimators of the number of objects per area unbiased by edge effects.

H J Gundersen.   

Abstract

A survey is given of principles for obtaining an estimate of the numerical density of profiles not biased by the edge effect in planar samples. Various practical problems of implementation of the principles are discussed. None of the methods represent the ideal combination of independence of assumptions concerning both profiles and frame as well as independence of information external to the frame. The counting rules usually employed in the determination of numerical density are biased and also unnecessarily complicated. For manual work only two unbiased principles apply. The choice between them is mainly determined by the ease by which they are implemented.

Mesh:

Year:  1978        PMID: 366342

Source DB:  PubMed          Journal:  Microsc Acta        ISSN: 0044-376X


  24 in total

1.  Is manual counting of corneal endothelial cell density in eye banks still acceptable? The French experience.

Authors:  G Thuret; C Manissolle; S Acquart; J-C Le Petit; J Maugery; L Campos-Guyotat; M J Doughty; P Gain
Journal:  Br J Ophthalmol       Date:  2003-12       Impact factor: 4.638

2.  Zinc and glutamine improve brain development in suckling mice subjected to early postnatal malnutrition.

Authors:  Fernando V L Ladd; Aliny A B L Ladd; Antônio Augusto C M Ribeiro; Samuel B C Costa; Bruna P Coutinho; George André S Feitosa; Geanne M de Andrade; Carlos Maurício de Castro-Costa; Carlos Emanuel C Magalhães; Ibraim C Castro; Bruna B Oliveira; Richard L Guerrant; Aldo Angelo M Lima; Reinaldo B Oriá
Journal:  Nutrition       Date:  2010-04-03       Impact factor: 4.008

3.  A comparison of model-based (2D) and design-based (3D) stereological methods for estimating cell number in the substantia nigra pars compacta (SNpc) of the C57BL/6J mouse.

Authors:  Z C Baquet; D Williams; J Brody; R J Smeyne
Journal:  Neuroscience       Date:  2009-04-17       Impact factor: 3.590

4.  Stability in synapse number and size at 2 hr after long-term potentiation in hippocampal area CA1.

Authors:  K E Sorra; K M Harris
Journal:  J Neurosci       Date:  1998-01-15       Impact factor: 6.167

5.  Adaptation of the disector method to rare small organelles in TEM sections exemplified by counting synaptic bodies in the rat pineal gland.

Authors:  H Jastrow; M A Von Mach; L Vollrath
Journal:  J Anat       Date:  1997-10       Impact factor: 2.610

6.  Prolonged maternal separation induces undernutrition and systemic inflammation with disrupted hippocampal development in mice.

Authors:  Ítalo Leite Figueiredo; Priscila B Frota; Davi G da Cunha; Ramon da Silva Raposo; Kildere M Canuto; Geanne M de Andrade; Nuno Sousa; Sean R Moore; Gregory M Anstead; Jacqueline I Alvarez-Leite; Richard L Guerrant; Reinaldo B Oriá
Journal:  Nutrition       Date:  2016-03-06       Impact factor: 4.008

7.  A volumetric screening procedure for the Göttingen minipig brain.

Authors:  J Jelsing; A K Olsen; P Cumming; A Gjedde; A K Hansen; S Arnfred; R Hemmingsen; B Pakkenberg
Journal:  Exp Brain Res       Date:  2005-01-25       Impact factor: 1.972

8.  Electron microscopic stereological study of collagen fibrils in bovine articular cartilage: volume and surface densities are best obtained indirectly (from length densities and diameters) using isotropic uniform random sampling.

Authors:  T K Långsjö; M Hyttinen; A Pelttari; K Kiraly; J Arokoski; H J Helminen
Journal:  J Anat       Date:  1999-08       Impact factor: 2.610

9.  Calibration of the stereological estimation of the number of myelinated axons in the rat sciatic nerve: a multicenter study.

Authors:  S Kaplan; S Geuna; G Ronchi; M B Ulkay; C S von Bartheld
Journal:  J Neurosci Methods       Date:  2010-01-12       Impact factor: 2.390

10.  Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11.

Authors:  H Wildiers; G Guetens; G De Boeck; E Verbeken; B Landuyt; W Landuyt; E A de Bruijn; A T van Oosterom
Journal:  Br J Cancer       Date:  2003-06-16       Impact factor: 7.640

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