Literature DB >> 3662824

The feasibility of sensitization studies using fewer test animals.

T Hofmann1, K H Diehl, K H Leist, W Weigand.   

Abstract

The possibility of reducing the number of animals in sensitization studies (maximization method) is discussed on the basis of results from 20 sensitization tests. It appears that the number of test animals in sensitization studies may be reduced to ten treated animals and five control animals without prejudice to the quality of the test.

Mesh：

Year:  1987        PMID： 3662824     DOI： 10.1007/bf00302393

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  2 in total

1.  The identification of contact allergens by animal assay. The guinea pig maximization test.

Authors:  B Magnusson; A M Kligman
Journal:  J Invest Dermatol       Date:  1969-03       Impact factor: 8.551

2.  Identification of contact sensitizers by animal assay.

Authors:  B Magnusson
Journal:  Contact Dermatitis       Date:  1980-01       Impact factor: 6.600
  2 in total
  1 in total

1.  Guinea pig maximization test for skin sensitisation: the use of fewer test animals.

Authors:  R O Shillaker; G M Bell; J T Hodgson; M D Padgham
Journal:  Arch Toxicol       Date:  1989       Impact factor: 5.153
  1 in total

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