Literature DB >> 3662823

The effect of a lipid suspension on amitriptyline disposition.

N A Minton1, A G Goode, J A Henry.   

Abstract

A 5-h infusion of a lipid suspension or saline was given on separate occasions to four healthy volunteers taking amitriptyline. Mean plasma levels of amitriptyline plus nortriptyline were 14% higher at the end of the lipid infusion but the difference was not statistically significant. Infusion of a lipid suspension is unlikely to materially affect the severity of amitriptyline intoxication.

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Year:  1987        PMID: 3662823     DOI: 10.1007/bf00302392

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN: 0340-5761            Impact factor:   5.153


  10 in total

1.  Reversal of advanced digoxin intoxication with Fab fragments of digoxin-specific antibodies.

Authors:  T W Smith; E Haber; L Yeatman; V P Butler
Journal:  N Engl J Med       Date:  1976-04-08       Impact factor: 91.245

2.  Influence of emulsified fat on chlorpromazine availability in rabbit blood.

Authors:  J Krieglstein; A Meffert; D H Niemeyer
Journal:  Experientia       Date:  1974-08-15

3.  [Studies on the fate of the antidepressant amitriptyline in the organism of the rat and man].

Authors:  E Eschenhof; J Rieder
Journal:  Arzneimittelforschung       Date:  1969-06

4.  Distribution and fate of C-14-amitriptyline in mice and rats.

Authors:  G B Cassano; S E Sjöstrand; E Hansson
Journal:  Psychopharmacologia       Date:  1965-06-01

5.  Simplified method for monitoring tricyclic antidepressant therapy using gas--liquid chromatography with nitrogen detection.

Authors:  S Dawling; R A Braithwaite
Journal:  J Chromatogr       Date:  1978-11-01

Review 6.  Poisoning due to tricyclic antidepressant overdosage. Clinical presentation and treatment.

Authors:  P Crome
Journal:  Med Toxicol       Date:  1986 Jul-Aug

7.  Tricyclic antidepressant poisoning. Management of arrhythmias.

Authors:  P R Pentel; N L Benowitz
Journal:  Med Toxicol       Date:  1986 Mar-Apr

8.  Circumstances surrounding deaths from accidental poisoning 1974-80.

Authors:  A W Craft
Journal:  Arch Dis Child       Date:  1983-07       Impact factor: 3.791

9.  Treatment of antidepressant poisoning with resin hemoperfusion.

Authors:  A Heath; I Wickström; E Mårtensson; J Ahlmén
Journal:  Hum Toxicol       Date:  1982-10

10.  The treatment of tricyclic antidepressant overdose with repeated charcoal.

Authors:  C M Swartz; A Sherman
Journal:  J Clin Psychopharmacol       Date:  1984-12       Impact factor: 3.153

  10 in total
  7 in total

1.  Cardiac depression induced by cocaine or cocaethylene is alleviated by lipid emulsion more effectively than by sulfobutylether-β-cyclodextrin.

Authors:  Michael R Fettiplace; Adrian Pichurko; Richard Ripper; Bocheng Lin; Katarzyna Kowal; Kinga Lis; David Schwartz; Douglas L Feinstein; Israel Rubinstein; Guy Weinberg
Journal:  Acad Emerg Med       Date:  2015-04-23       Impact factor: 3.451

Review 2.  Intravenous fat emulsion: a potential novel antidote.

Authors:  Danielle E Turner-Lawrence; William Kerns Ii
Journal:  J Med Toxicol       Date:  2008-06

3.  The role of fat emulsion therapy in a rodent model of propranolol toxicity: a preliminary study.

Authors:  Grant Cave; Martyn G Harvey; Craig D Castle
Journal:  J Med Toxicol       Date:  2006-03

4.  Asystole immediately following intravenous fat emulsion for overdose.

Authors:  Jon B Cole; Samuel J Stellpflug; Kristin M Engebretsen
Journal:  J Med Toxicol       Date:  2014-09

Review 5.  Should we consider the infusion of lipid emulsion in the resuscitation of poisoned patients?

Authors:  Grant Cave; Martyn G Harvey
Journal:  Crit Care       Date:  2014-07-30       Impact factor: 9.097

6.  Physiologically based pharmacokinetic-quantitative systems toxicology and safety (PBPK-QSTS) modeling approach applied to predict the variability of amitriptyline pharmacokinetics and cardiac safety in populations and in individuals.

Authors:  Zofia Tylutki; Aleksander Mendyk; Sebastian Polak
Journal:  J Pharmacokinet Pharmacodyn       Date:  2018-06-25       Impact factor: 2.745

7.  Esmolol for intractable ventricular arrhythmias in major amitriptyline toxicity.

Authors:  Peter Garrett; Steven Klupfel
Journal:  BMJ Case Rep       Date:  2022-07-22
  7 in total

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