Literature DB >> 3662280

Fatal Rhizopus infections in hemodialysis patients receiving deferoxamine.

D W Windus1, T J Stokes, B A Julian, A Z Fenves.   

Abstract

Four hemodialysis patients receiving deferoxamine for metal overload had fatal rhinocerebral rhizopus infections. Serious fungal infections are not commonly seen in patients on dialysis, and none of these patients had the usual risk factors for rhizopus infection. Deferoxamine is being used with increased frequency in dialysis patients for aluminum and iron overload states. We propose that there is a link between the deferoxamine therapy and this unusual infection. Deferoxamine may serve as a specific growth factor for Rhizopus species or may alter host immune function. We suggest searching for fungal organisms in patients with unexplained illnesses receiving deferoxamine.

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Year:  1987        PMID： 3662280     DOI： 10.7326/0003-4819-107-5-678

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN： 0003-4819            Impact factor:   25.391


  20 in total

1.  The Deferasirox-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) study: a randomized, double-blinded, placebo-controlled trial.

Authors:  Brad Spellberg; Ashraf S Ibrahim; Peter V Chin-Hong; Dimitrios P Kontoyiannis; Michele I Morris; John R Perfect; David Fredricks; Eric P Brass
Journal:  J Antimicrob Chemother       Date:  2011-09-20       Impact factor: 5.790

Review 2.  The spectrum of fungi that infects humans.

Authors:  Julia R Köhler; Arturo Casadevall; John Perfect
Journal:  Cold Spring Harb Perspect Med       Date:  2014-11-03       Impact factor: 6.915

3.  What treatment would you advise for a 1-year-old child with chronic renal failure who has been on aluminum hydroxide as a phosphate binder for 6 months and then develops epilepsy and is found to have a grossly raised plasma aluminum concentration?

Authors:  S P Andreoli; R W Chesney; I B Salusky; A B Sedman
Journal:  Pediatr Nephrol       Date:  1990-07       Impact factor: 3.714

4.  Pulmonary mucormycosis presenting as massive fatal hemoptysis in a hemodialytic patient with chronic renal failure.

Authors:  S Yagihashi; K Watanabe; K Nagai; M Okudaira
Journal:  Klin Wochenschr       Date:  1991-03-18

5.  Andrew Zoltan Fenves, MD: a conversation with the editor. Interview by William Clifford Roberts.

Authors:  Andrew Zoltan Fenves
Journal:  Proc (Bayl Univ Med Cent)       Date:  2004-07

Review 6.  Diagnosing fungal infections in immunocompromised hosts.

Authors:  C M Tang; J Cohen
Journal:  J Clin Pathol       Date:  1992-01       Impact factor: 3.411

Review 7.  Connecting iron acquisition and biofilm formation in the ESKAPE pathogens as a strategy for combatting antibiotic resistance.

Authors:  Savannah J Post; Justin A Shapiro; William M Wuest
Journal:  Medchemcomm       Date:  2019-03-21       Impact factor: 3.597

8.  Gastric mucormycosis due to Rhizopus oryzae in a renal transplant recipient.

Authors:  S Winkler; S Susani; B Willinger; R Apsner; A R Rosenkranz; R Pötzi; G A Berlakovich; E Pohanka
Journal:  J Clin Microbiol       Date:  1996-10       Impact factor: 5.948

9.  Fatal fungal peritonitis in an adolescent on continuous ambulatory peritoneal dialysis: association with deferoxamine.

Authors:  M Nakamura; W B Weil; D B Kaufman
Journal:  Pediatr Nephrol       Date:  1989-01       Impact factor: 3.714

10.  Bacterial Siderophores Hijack Neutrophil Functions.

Authors:  Piu Saha; Beng San Yeoh; Rodrigo A Olvera; Xia Xiao; Vishal Singh; Deepika Awasthi; Bhagawat C Subramanian; Qiuyan Chen; Madhu Dikshit; Yanming Wang; Carole A Parent; Matam Vijay-Kumar
Journal:  J Immunol       Date:  2017-04-21       Impact factor: 5.422
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