Literature DB >> 3661772

Inadequate plasma concentrations in some high-dose methadone maintenance patients.

F S Tennant1.   

Abstract

The author studied 18 heroin addicts who had been maintained on 80 mg/day of methadone and who abused drugs or alcohol. His findings suggest that in some cases of aberrant methadone metabolism, the dose can be raised to achieve plasma concentrations adequate to eliminate drug and alcohol abuse.

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Year:  1987        PMID: 3661772     DOI: 10.1176/ajp.144.10.1349

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  9 in total

1.  Psychophysiological reactions in methadone maintenance patients do not correlate with methadone plasma levels.

Authors:  N Loimer; R Schmid; J Grünberger; R Jagsch; L Linzmayer; O Presslich
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

Review 2.  Methadone maintenance in the treatment of opioid dependence. A current perspective.

Authors:  J E Zweben; J T Payte
Journal:  West J Med       Date:  1990-05

Review 3.  Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence.

Authors:  Chin B Eap; Thierry Buclin; Pierre Baumann
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

4.  Steady-state pharmacokinetics of methadone in opioid addicts.

Authors:  K Wolff; A W Hay; D Raistrick; R Calvert
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953

5.  Heroin use during methadone maintenance treatment: the importance of methadone dose and cocaine use.

Authors:  D M Hartel; E E Schoenbaum; P A Selwyn; J Kline; K Davenny; R S Klein; G H Friedland
Journal:  Am J Public Health       Date:  1995-01       Impact factor: 9.308

Review 6.  Methadone maintenance treatment: an update.

Authors:  G Bertschy
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1995       Impact factor: 5.270

Review 7.  New Approaches in Drug Dependence: Opioids.

Authors:  Juliane Mielau; Marc Vogel; Stefan Gutwinski; Inge Mick
Journal:  Curr Addict Rep       Date:  2021-05-26

8.  In silico ordinary differential equation/partial differential equation hemodialysis model estimates methadone removal during dialysis.

Authors:  Oscar A Linares; William E Schiesser; Jeffrey Fudin; Thien C Pham; Jeffrey J Bettinger; Roy O Mathew; Annemarie L Daly
Journal:  J Pain Res       Date:  2015-07-22       Impact factor: 3.133

9.  Methadone Concentrations in Exhaled Breath Condensate, Serum and Urine of Patients Under Maintenance Treatment.

Authors:  Maryam Khoubnasabjafari; Khalil Ansarin; Vahid Jouyban-Gharamaleki; Vahid Panahi-Azar; Samin Hamidi; Zhila Azarmir; Abolghasem Jouyban
Journal:  Iran J Pharm Res       Date:  2017       Impact factor: 1.696

  9 in total

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