Literature DB >> 3660952

Determination of cocaine in human hair by gas chromatography/mass spectrometry.

S Balabanova1, J Homoki.   

Abstract

A qualitative method for the determination of cocaine alone without its metabolites in human hair by gas chromatography/mass spectrometry (GC/MS) was developed. The assay used helium as carrier gas, a 30-m bonded phase fused silica OV-1 capillary column, and solid injection at 290 degrees C evaporator temperature. The cocaine concentrations in hair were determined also by radioimmunoassay (RIA). The values obtained are the sum of cocaine and its metabolites. Both GC/MS and RIA meet the requirements for the determination of drug abuse by two different methods in forensic science.

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Year:  1987        PMID： 3660952     DOI： 10.1007/bf00201228

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN： 0044-3433


  12 in total

1.  Distribution and metabolism of cocaine in the dog and rabbit.

Authors:  L A WOODS; F G McMAHON; M H SEEVERS
Journal:  J Pharmacol Exp Ther       Date:  1951-02       Impact factor: 4.030

2.  Quantitative determination of cocaine and its metabolites benzoylecgonine and ecgonine by gas-liquid chromatography.

Authors:  J I Javaid; H Dekirmenjian; E G Brunngraber; J M Davis
Journal:  J Chromatogr       Date:  1975-07-02

3.  Detection of cocaine metabolite in perspiration stain, menstrual bloodstain, and hair.

Authors:  F P Smith; R H Liu
Journal:  J Forensic Sci       Date:  1986-10       Impact factor: 1.832

4.  The determination of cocaine and its major metabolite, benzoylecgonine, in postmortem fluids and tissues by computerized gas chromatography/mass spectrometry.

Authors:  E C Griesemer; Y Liu; R D Budd; L Raftogianis; T T Noguchi
Journal:  J Forensic Sci       Date:  1983-10       Impact factor: 1.832

5.  Radioimmunoassay of cocaine in hair: concise communication.

Authors:  W A Baumgartner; C T Black; P F Jones; W H Blahd
Journal:  J Nucl Med       Date:  1982-09       Impact factor: 10.057

6.  Gas chromatography-chemical ionization mass spectrometry of cocaine and its metabolites in biological fluids.

Authors:  D M Chinn; D J Crouch; M A Peat; B S Finkle; T A Jennison
Journal:  J Anal Toxicol       Date:  1980 Jan-Feb       Impact factor: 3.367

7.  Hair as the sample in assessing morphine and cocaine addiction.

Authors:  D Valente; M Cassini; M Pigliapochi; G Vansetti
Journal:  Clin Chem       Date:  1981-11       Impact factor: 8.327

8.  Disposition of cocaine in fatal poisoning in man.

Authors:  A Poklis; M A Mackell; M Graham
Journal:  J Anal Toxicol       Date:  1985 Sep-Oct       Impact factor: 3.367

9.  Mass spectrometric determination of cocaine and its biologically active metabolite, norcocaine, in human urine.

Authors:  S P Jindal; T Lutz; P Vestergaard
Journal:  Biomed Mass Spectrom       Date:  1978-12

10.  Radioimmunological determination of cocaine in human hair.

Authors:  S Balabanova; H Brunner; R Nowak
Journal:  Z Rechtsmed       Date:  1987
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  5 in total

1.  First identification of drugs in Egyptian mummies.

Authors:  S Balabanova; F Parsche; W Pirsig
Journal:  Naturwissenschaften       Date:  1992-08

2.  Detection of drugs in human hair for clinical and forensic applications.

Authors:  P Kintz; A Tracqui; P Mangin
Journal:  Int J Legal Med       Date:  1992       Impact factor: 2.686

3.  Deposition of cocaine in tissue after lethal and repeated sublethal administration to sheep.

Authors:  R Nowak; S Balabanova; H Brunner; J Homoki; B Bürger; G Reinhardt
Journal:  Z Rechtsmed       Date:  1988

Review 4.  Adherence Measurements in HIV: New Advancements in Pharmacologic Methods and Real-Time Monitoring.

Authors:  Jose R Castillo-Mancilla; Jessica E Haberer
Journal:  Curr HIV/AIDS Rep       Date:  2018-02       Impact factor: 5.071

5.  Hair analysis for drugs of abuse. V. The facility in incorporation of cocaine into hair over its major metabolites, benzoylecgonine and ecgonine methyl ester.

Authors:  Y Nakahara; T Ochiai; R Kikura
Journal:  Arch Toxicol       Date:  1992       Impact factor: 5.153
  5 in total

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